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Cardiothoracic ratio, malnutrition, inflammation, and two-year mortality in non-diabetic patients on maintenance hemodialysis.

Author(s): Kuan-Hsing Chen, Dan-Tzu Lin-Tan, Wen-Hung Huang, Cheng-Chieh Hung, Chiz-Tzung Chang, Jeng-Yi Huang, Ja-Liang Lin

Publication date: 2007-12-31

Journal: Kidney & blood pressure research

Keywords: Cardiovascular Diseases, diagnosis, mortality, Diagnostic Techniques, Cardiovascular, standards, Female, Follow-Up Studies, Humans, Hypertrophy, Left Ventricular, Inflammation, Kidney Failure, Chronic, Male, Malnutrition, Middle Aged, Predictive Value of Tests, Radiography, Thoracic, methods, Renal Dialysis, Survival Rate, Ventricular Dysfunction, Left

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Abstract

Cardiothoracic ratio (CTR) is associated with left ventricular mass, left ventricular systolic dysfunction and mortality in patients with hypertension or chronic cardiovascular disease. The clinical significance of CTR in non-diabetic maintenance hemodialysis (MHD) patients remains unclear. 468 non-diabetic MHD patients were enrolled. Geographic, hematological, biochemical and dialysis-related data were obtained. The patients were analyzed for nutritional and inflammatory markers as well as CTR. All patients were followed up for 2 years to investigate the risks for mortality. Chi-square analysis showed that the incidence of malnutrition and inflammation was significantly higher in patients with CTR >60% than in patients with CTR 50%. (c) 2008 S. Karger AG, Basel.

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Most cited references 26

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John M. Tauber, S. Shalet, J. P. Monson … (2005)

The European Society for Paediatric Endocrinology held a consensus workshop in Manchester, UK in December 2003 to discuss issues relating to the care of GH-treated patients in the transition from paediatric to adult life. Clinicians experienced in the care of paediatric and adult patients on GH treatment, from a wide range of countries, as well as medical representatives from the pharmaceutical manufacturers of GH participated.