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      Number of Persons With Symptomatic Knee Osteoarthritis in the US: Impact of Race and Ethnicity, Age, Sex, and Obesity.

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          Abstract

          The prevalence of symptomatic knee osteoarthritis (OA) has been increasing over the past several decades in the US, concurrent with an aging population and the growing obesity epidemic. We quantify the impact of these factors on the number of persons with symptomatic knee OA in the early decades of the 21st century.

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          The effect of osteoarthritis definition on prevalence and incidence estimates: a systematic review.

          D. Pereira, B Peleteiro, J. Araujo … (2011)
          To understand the differences in prevalence and incidence estimates of osteoarthritis (OA), according to case definition, in knee, hip and hand joints. A systematic review was carried out in PUBMED and SCOPUS databases comprising the date of publication period from January 1995 to February 2011. We attempted to summarise data on the incidence and prevalence of OA according to different methods of assessment: self-reported, radiographic and symptomatic OA (clinical plus radiographic). Prevalence estimates were combined through meta-analysis and between-study heterogeneity was quantified. Seventy-two papers were reviewed (nine on incidence and 63 on prevalence). Higher OA prevalences are seen when radiographic OA definition was used for all age groups. Prevalence meta-analysis showed high heterogeneity between studies even in each specific joint and using the same OA definition. Although the knee is the most studied joint, the highest OA prevalence estimates were found in hand joints. OA of the knee tends to be more prevalent in women than in men independently of the OA definition used, but no gender differences were found in hip and hand OA. Insufficient data for incidence studies didn't allow us to make any comparison according to joint site or OA definition. Radiographic case definition of OA presented the highest prevalences. Within each joint site, self-reported and symptomatic OA definitions appear to present similar estimates. The high heterogeneity found in the studies limited further conclusions. Copyright © 2011 Osteoarthritis Research Society International. Published by Elsevier Ltd. All rights reserved.
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            Lifetime medical costs of knee osteoarthritis management in the United States: impact of extending indications for total knee arthroplasty.

            Elena Losina, A. Paltiel, Alexander Weinstein … (2015)
            The impact of increasing utilization of total knee arthroplasty (TKA) on lifetime costs in persons with knee osteoarthritis (OA) is understudied.
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              Lifetime risk and age at diagnosis of symptomatic knee osteoarthritis in the US.

              Elena Losina, Alexander Weinstein, William Reichmann … (2013)
              To estimate the incidence and lifetime risk of diagnosed symptomatic knee osteoarthritis (OA) and the age at diagnosis of knee OA based on self-reports in the US population.
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                Author and article information

                Journal
                Journal ID (iso-abbrev): Arthritis Care Res (Hoboken)
                Title: Arthritis care & research
                Publisher: Wiley-Blackwell
                ISSN (Electronic): 2151-4658
                ISSN (Print): 2151-464X
                Publication date (Electronic): Dec 2016
                Volume: 68
                Issue: 12
                Affiliations
                [1 ] Brigham and Women's Hospital, Boston, Massachusetts.
                [2 ] Brigham and Women's Hospital, Harvard Medical School, and Harvard T. H. Chan School of Public Health, Boston, Massachusetts.
                [3 ] Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.
                [4 ] Philip R. Lee Institute for Health Policy Studies and Rosalind Russell/Ephraim P. Engleman Rheumatology Research Center, University of California, San Francisco.
                [5 ] Institute of Bone and Joint Research, Kolling Institute, University of Sydney, Sydney, New South Wales, Australia, and Royal North Shore Hospital, St. Leonards, New South Wales, Australia.
                [6 ] Wake Forest School of Medicine, Wake Forest University, Winston-Salem, North Carolina.
                [7 ] Yale School of Medicine and Yale-New Haven Hospital, New Haven, Connecticut, and Veterans Affairs Connecticut Healthcare System, West Haven, Connecticut.
                [8 ] Brigham and Women's Hospital, Harvard Medical School, and Boston University School of Public Health, Boston, Massachusetts.
                Article
                Mid ID: NIHMS775448
                DOI: 10.1002/acr.22897
                PMC ID: 5319385
                PubMed ID: 27014966
                SO-VID: da19551b-3764-4b00-b0bf-3b96797d47cc
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