53
views
0
recommends
+1 Recommend
1 collections
    1
    shares
      • Record: found
      • Abstract: found
      • Article: not found
      Is Open Access

      Grand Challenges in Nutrition

      Frontiers in Nutrition
      Frontiers Media S.A.
      nutrition, food, eating behavior, obesity, malnutrition, metabolism, food supply, hunger

      Read this article at

      ScienceOpenPublisherPMC
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          No subject pertains more to human life than nutrition. Biologically, this statement is evident. Historically, we are aware of the impact nutrition can have on entire cultures as a result of abundant or diminished and impaired or restricted food supply. Nutrition and food always have been at the heart of human life. Owing to the significance of food and nutrition, the world is facing a continued set of challenges and Frontiers in Nutrition is determined to address all of them. Specifically, in an ever more densely populated world, we will continue to be confronted by problems of hunger on a massive scale, hence Eradicating Extreme Poverty and Hunger is the number one Millenium Development Goal of the UN (1) and the key issue for the post-2015 development agenda (2). At the same time, we observe a growing obesity epidemic in both developed countries and in emerging economies at an alarming velocity. Hunger, malnutrition, and obesity are linked to a variety of health and societal issues, such as impaired development, diabetes, Alzheimer’s disease, and allergies, as well as an environmental burden and impaired economic performance – to name just a few. Yet, at the beginning of the twenty-first century, we are also embracing an era full of opportunity with breathtaking advances in science, agriculture, commerce, and global interaction. So, how do these challenges in the field of nutrition translate into tangible challenges for Frontiers in Nutrition? Ultimately, Frontiers’ ambition has to be directed toward the alleviation of hunger, malnutrition, and obesity. With a sober mindset this can be achieved through the publication of credible, rigorous, and meaningful science within the specialty sections of the journal. More Science is Needed Over the past decades, general awareness about the biological aspects of nutrition has grown. The over-simplistic view that nutrition refers mainly to the supply of macro- and micro-nutrients through carbohydrates, fat, protein, and a mix of vitamins and minerals to provide building blocks and energy has been replaced by novel approaches that aim to introduce a substantially more detailed level of understanding. Today, we are more conscious of the complex nature of the changing demands of our bodies in different environments and situations and, in particular, as we grow older (3). In addition, mounting scientific evidence indicates that certain foods can help treat diseases and are already playing a strong role in the prevention of diseases (4–6). In recent years, research on nutrition and nutrient requirements has taken increasingly into account personalized and genetic information with the goal to cater directly to individual needs either based on different genotypes or on different metabolic states of the body. However, more needs to be done and complex scientific questions need to be answered. In the overall context of nutrition, an opportunity and an equal need is emerging for ground breaking and integrated fundamental science on nutrition physiology, brain mechanisms, overall health, childhood development, and nutrition methodology (7, 8). For example, in the specific case of weight management even a few fundamental questions can already provide ample work for years to come: What are the mechanisms of food perception and how can the molecular mechanisms of hunger and satiety homeostasis in our brain be integrated with food intake behavior? What can we learn from the population dynamics of about 2 kg of intestinal microbiota to formulate tangible advice for healthy nutrition? (4). Nutrition in Society, Private, and Public Sector Nutrition is involved with culture, infrastructure, and economic status and as such it is a prerequisite for and a result of our lifestyle at the same time. The world is changing and so will the actual diets, and the food related behaviors change – for better or worse. Centuries ago, adequate nutrition was a question of appropriate food supply within well-defined geographies and populations. We have come a long way from being hunters and gatherers to the formation of today’s complex societies driving agriculture, local food manufacturing, and a globally acting food industry. With the exponential growth of an aging world population and society’s desire to fight malnutrition and climate change, new demands arise for the sourcing and distribution of food. So, where does our food come from and who is responsible for it? For example, the spice trade likely accounts for the first documented long-distance transport of food ingredients across the globe. But is it still sustainable today to ship food around the world? And how do recommended dietary guidelines impact the carbon footprint on our ecosystems? With the key objective of feeding the planet, it is crucial to establish a meaningful and forward-looking framework among universities, the private sector, regulatory bodies, and NGOs in order to ensure adequate nutrition for all – a topic that is too important to be handled behind closed doors. Frontiers in Nutrition In the globalized world of the twenty-first century transparence and communication are the key determinants behind driving change. And change is needed. As scientific funding is becoming scarcer, increased scrutiny on the “meaningfulness” of scientific research and publication will become the dominant factor. Frontiers in Nutrition will address the need for science that is asking the right questions in a vast and complex network of open issues around nutrition. The challenge will be to illustrate scientific results in a new light, to integrate these results with interdisciplinary problems and to conclude on actions that will have an impact on the global agenda.

          Related collections

          Most cited references5

          • Record: found
          • Abstract: found
          • Article: not found

          Recruiting adaptive cellular stress responses for successful brain ageing.

          Successful ageing is determined in part by genetic background, but also by experiential factors associated with lifestyle and culture. Dietary, behavioural and pharmacological interventions have been identified as potential means to slow brain ageing and forestall neurodegenerative disease. Many of these interventions recruit adaptive cellular stress responses to strengthen neuronal networks and enhance plasticity. In this Science and Society article, we describe several determinants of healthy and pathological brain ageing, with insights into how these processes are accelerated or prevented. We also describe the mechanisms underlying the neuroprotective actions of exercise and nutritional interventions, with the goal of recruiting these molecular targets for the treatment and prevention of neurodegenerative disease.
            Bookmark
            • Record: found
            • Abstract: found
            • Article: found
            Is Open Access

            Systems solutions by lactic acid bacteria: from paradigms to practice

            Lactic acid bacteria are among the powerhouses of the food industry, colonize the surfaces of plants and animals, and contribute to our health and well-being. The genomic characterization of LAB has rocketed and presently over 100 complete or nearly complete genomes are available, many of which serve as scientific paradigms. Moreover, functional and comparative metagenomic studies are taking off and provide a wealth of insight in the activity of lactic acid bacteria used in a variety of applications, ranging from starters in complex fermentations to their marketing as probiotics. In this new era of high throughput analysis, biology has become big science. Hence, there is a need to systematically store the generated information, apply this in an intelligent way, and provide modalities for constructing self-learning systems that can be used for future improvements. This review addresses these systems solutions with a state of the art overview of the present paradigms that relate to the use of lactic acid bacteria in industrial applications. Moreover, an outlook is presented of the future developments that include the transition into practice as well as the use of lactic acid bacteria in synthetic biology and other next generation applications.
              Bookmark
              • Record: found
              • Abstract: not found
              • Article: not found

              Implausible results in human nutrition research.

                Bookmark

                Author and article information

                Journal
                25988106
                4429647
                10.3389/fnut.2014.00001
                http://creativecommons.org/licenses/by/3.0/

                nutrition,food,eating behavior,obesity,malnutrition,metabolism,food supply,hunger

                Comments

                Comment on this article