Variants of the elastin (ELN) gene and susceptibility to intracranial aneurysm: a synthesis of genetic association studies using a genetic model-free approach.

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Abstract

The presence of an intracranial aneurysm (IA) is thought to have a genetic origin. The genetic association studies (GAS) that investigated the association between IA and elastin gene (ELN) variants have produced contradictory or inconclusive results.

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Journal ID (iso-abbrev): Int. J. Neurosci.

Title: The International journal of neuroscience

Publisher: Informa UK Limited

ISSN (Electronic): 1563-5279

ISSN (Print): 0020-7454

Publication date (Electronic): Jul 2017

Volume: 127

Issue: 7

Affiliations

[1 ] a Department of Neurosurgery , University of Thessaly School of Medicine , Larissa , Greece.

[2 ] b Vascular Surgery Department , University of Thessaly School of Medicine , Larissa , Greece.

[3 ] c Department of Biomathematics , University of Thessaly School of Medicine , Larissa , Greece.

[4 ] d Department of Neurosurgery , University Hospitals of Cleveland, St. Vincent's Hospital Manhattan, Weill Cornell Medical College , OH , USA.

[5 ] e Department of Neurology , University of Thessaly School of Medicine , Larissa , Greece.

[6 ] f Institute for Clinical Research and Health Policy Studies, Tufts Medical Center, Tufts University School of Medicine , Boston , MA , USA.

[7 ] g BECRO , Athens , Greece.

Article

DOI: 10.1080/00207454.2016.1212027

PubMed ID: 27687579

SO-VID: 000f37ab-a3e1-4696-9dcd-101badb49161

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Keywords: ELN,elastin gene,genetic association,intracranial aneurysm,intracranial hemorrhage,subarachnoid hemorrhage

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Keywords: ELN, elastin gene, genetic association, intracranial aneurysm, intracranial hemorrhage, subarachnoid hemorrhage

Variants of the elastin (ELN) gene and susceptibility to intracranial aneurysm: a synthesis of genetic association studies using a genetic model-free approach.

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