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      Variants of the elastin (ELN) gene and susceptibility to intracranial aneurysm: a synthesis of genetic association studies using a genetic model-free approach.

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          Abstract

          The presence of an intracranial aneurysm (IA) is thought to have a genetic origin. The genetic association studies (GAS) that investigated the association between IA and elastin gene (ELN) variants have produced contradictory or inconclusive results.

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          Author and article information

          Journal
          Int. J. Neurosci.
          The International journal of neuroscience
          Informa UK Limited
          1563-5279
          0020-7454
          Jul 2017
          : 127
          : 7
          Affiliations
          [1 ] a Department of Neurosurgery , University of Thessaly School of Medicine , Larissa , Greece.
          [2 ] b Vascular Surgery Department , University of Thessaly School of Medicine , Larissa , Greece.
          [3 ] c Department of Biomathematics , University of Thessaly School of Medicine , Larissa , Greece.
          [4 ] d Department of Neurosurgery , University Hospitals of Cleveland, St. Vincent's Hospital Manhattan, Weill Cornell Medical College , OH , USA.
          [5 ] e Department of Neurology , University of Thessaly School of Medicine , Larissa , Greece.
          [6 ] f Institute for Clinical Research and Health Policy Studies, Tufts Medical Center, Tufts University School of Medicine , Boston , MA , USA.
          [7 ] g BECRO , Athens , Greece.
          Article
          10.1080/00207454.2016.1212027
          27687579

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