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      Sick Building Syndrome by Indoor Air Pollution in Dalian, China

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          Abstract

          This study assessed subjective symptoms related to indoor concentrations of chemicals among residents in a housing estate in Dalian, China, where indoor air pollution by interior decoration materials has recently become a major health problem. Fifty-nine males and 50 females were surveyed for their symptoms related to sick building syndrome. Formaldehyde (HCHO), NO 2, and volatile organic compounds (VOCs) in their dwellings were collected using a diffusion sampler and measured by GC/MS. For residents with one or more symptoms in the past, HCHO, butanol or 1,2-dichloroethane concentrations were significantly greater in their bedrooms or kitchens compared with those of subjects without previous symptoms. For residents with one or more symptoms at the time of the study, 1,1,1-trichloroethane, xylene, butanol, methyl isobutyl ketone, and styrene concentrations in their bedrooms or kitchens were significantly greater compared with those of residents without symptoms. HCHO, NO 2, and VOCs were detected in all rooms, but their levels were lower than the guideline values except for HCHO in two rooms. Chemical substances from interior decoration materials at indoor air levels lower than their guideline values might have affected the health status of residents.

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          Association of domestic exposure to volatile organic compounds with asthma in young children.

          To investigate the association between domestic exposure to volatile organic compounds (VOCs) and asthma in young children. A population based case-control study was conducted in Perth, Western Australia in children aged between 6 months and 3 years. Cases (n = 88) were children recruited at Princess Margaret Hospital accident and emergency department and discharged with asthma as the primary diagnosis; 104 controls consisted of children from the same age group without an asthma diagnosis identified through the Health Department of Western Australia. Information regarding the health status of the study children and characteristics of the home was collected using a standardised questionnaire. Exposure to VOCs, average temperature and relative humidity were measured in winter and summer in the living room of each participating household. Cases were exposed to significantly higher VOC levels (microg/m3) than controls (p<0.01). Most of the individual VOCs appeared to be significant risk factors for asthma with the highest odds ratios for benzene followed by ethylbenzene and toluene. For every 10 unit increase in the concentration of toluene and benzene (microg/m3) the risk of having asthma increased by almost two and three times, respectively. Domestic exposure to VOCs at levels below currently accepted recommendations may increase the risk of childhood asthma. Measurement of total VOCs may underestimate the risks associated with individual compounds.
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            Domestic exposure to formaldehyde significantly increases the risk of asthma in young children.

            Concern has arisen in recent years about indoor air pollution as a risk factor for asthma. Formaldehyde exposure was examined in relation to asthma among young children (between 6 months and 3 yrs old) in a population-based control study carried out in Perth, Western Australia, between 1997-1999. An association between exposure to formaldehyde and asthma in young children has been suggested. Cases (n=88), whose parents were recruited at Princess Margaret Hospital Accident and Emergency Dept (Perth, Western Australia), were children discharged with asthma as the primary diagnosis. Controls (n=104), who were children in the same age group without asthma diagnosed by a doctor, were identified from birth records through the Health Dept of Western Australia (Perth, Western Australia). Health outcomes for the children were studied using a respiratory questionnaire and skin-prick tests. Formaldehyde, average temperature and relative humidity were measured on two occasions, winter (July-September 1998) and summer (December 1998-March 1999) in the child's bedroom and in the living room. The study found seasonal differences in formaldehyde levels in the children's bedrooms and living rooms with significantly greater formaldehyde exposure during the summer period for case and control subjects. The generalised estimating equation model showed that children exposed to formaldehyde levels of > or = 60 microg x m(-3) are at increased risk of having asthma. The results suggest that domestic exposure to formaldehyde increases the risk of childhood asthma.
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              Asthmatic Symptoms among Pupils in Relation to Winter Indoor and Outdoor Air Pollution in Schools in Taiyuan, China

              Background There are few studies on associations between children’s respiratory heath and air pollution in schools in China. The industrial development and increased traffic may affect the indoor exposure to air pollutants in school environment. Moreover, there is a need to study respiratory effects of environmental tobacco smoke (ETS) and emissions from new building materials in homes in China. Objectives We studied the associations between pupils’ asthmatic symptoms and indoor and outdoor air pollution in schools, as well as selected home exposures, in a coal-burning city in north China. Methods A questionnaire survey was administered to pupils (11–15 years of age) in 10 schools in urban Taiyuan, collecting data on respiratory health and selected home environmental factors. Indoor and outdoor school air pollutants and climate factors were measured in winter. Results A total of 1,993 pupils (90.2%) participated; 1.8% had cumulative asthma, 8.4% wheezing, 29.8% had daytime attacks of breathlessness. The indoor average concentrations of sulfur dioxide, nitrogen dioxide, ozone, and formaldehyde by class were 264.8, 39.4, 10.1, and 2.3 μg/m3, respectively. Outdoor levels were two to three times higher. Controlling for possible confounders, either wheeze or daytime or nocturnal attacks of breathlessness were positively associated with SO2, NO2, or formaldehyde. In addition, ETS and new furniture at home were risk factors for wheeze, daytime breathlessness, and respiratory infections. Conclusions Indoor chemical air pollutants of mainly outdoor origin could be risk factors for pupils’ respiratory symptoms at school, and home exposure to ETS and chemical emissions from new furniture could affect pupils’ respiratory health.
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                Author and article information

                Journal
                Int J Environ Res Public Health
                Int J Environ Res Public Health
                ijerph
                International Journal of Environmental Research and Public Health
                MDPI
                1661-7827
                1660-4601
                11 April 2013
                April 2013
                : 10
                : 4
                : 1489-1504
                Affiliations
                [1 ]Department of Epidemiology and Environmental Health, Juntendo University Faculty of Medicine, Bunkyo-ku, Tokyo 113-8421, Japan; E-Mails: kakuchina_1@ 123456yahoo.co.jp (P.G.); fkitamu@ 123456juntendo.ac.jp (F.K.)
                [2 ]Faculty of Environmental and Information Science, Yokkaichi University, 1200 Kayouchyou, Yokkaichi, Mie 512-8512, Japan
                [3 ]Department of Public Health and Occupational Medicine, Mie University Graduate School of Medicine, Tsu, Mie 514-8507, Japan
                [4 ]Department of Occupational and Environmental Health, Dalian Medical University, Dalian, LiaoNing 116044, China; E-Mail: piaofengjp@ 123456yahoo.co.jp
                [5 ]Nagoya City Public Health Research Institute, Mizuho-ku, Nagoya, Aichi 467-8615, Japan; E-Mail: ehdeiken@ 123456sa.starcat.ne.jp
                [6 ]Department of Occupational and Environmental Health, Nagoya University Graduate School of Medicine, Showa-ku, Nagoya, Aichi 466-8550, Japan; E-Mails: romenraihan@ 123456yahoo.com (M.K.); tnasu23@ 123456med.nagoya-u.ac.jp (T.N.)
                [7 ]Department of Occupational and Environmental Health, Nagoya City University Graduate School of Medical Sciences, Mizuho-ku, Nagoya, Aichi 467-8601, Japan; E-Mail: kamijima@ 123456med.nagoya-cu.ac.jp
                Author notes
                [* ] Author to whom correspondence should be addressed. E-Mail: kyokoya@ 123456juntendo.ac.jp ; Tel.: +81-03-5802-1046; Fax: +81-03-3812-1026.
                Article
                ijerph-10-01489
                10.3390/ijerph10041489
                3709330
                23579877
                0012b090-2711-484e-a8b9-1d819a3c6090
                © 2013 by the authors; licensee MDPI, Basel, Switzerland.

                This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license ( http://creativecommons.org/licenses/by/3.0/).

                History
                : 10 February 2013
                : 28 March 2013
                : 03 April 2013
                Categories
                Article

                Public health
                sick building syndrome,indoor air pollution,china,formaldehyde,volatile organic compound

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