MiR-145 detection in urinary extracellular vesicles increase diagnostic efficiency of prostate cancer based on hydrostatic filtration dialysis method.

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Abstract

Extracellular vesicles (EVs) can be detected in body fluids and may serve as disease biomarkers. Increasing evidence suggests that circulating miRNAs in serum and urine may be potential non-invasive biomarkers for prostate cancer (PCa). In the present study, we aimed to investigate whether hydrostatic filtration dialysis (HFD) is suitable for urinary EVs (UEVs) isolation and whether such reported PCa-related miRNAs can be detected in UEVs as PCa biomarkers.

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Journal

Journal ID (iso-abbrev): Prostate

Title: The Prostate

Publisher: Wiley

ISSN (Electronic): 1097-0045

ISSN (Print): 0270-4137

Publication date (Electronic): Jul 2017

Volume: 77

Issue: 10

Affiliations

[1 ] Department of Laboratory Medicine, Nanfang Hospital, Southern Medical University, Guangzhou, China.

[2 ] Department of Clinical Laboratory, Zhongnan Hospital, Wuhan University, Wuhan, Hubei, China.

Article

DOI: 10.1002/pros.23376

PubMed ID: 28617988

SO-VID: 0032674a-f669-4fc1-97f9-7fda9737879e

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Keywords: extracellular vesicles,hydrostatic filtration dialysis,miRNA,prostate cancer,urinary

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Keywords: extracellular vesicles, hydrostatic filtration dialysis, miRNA, prostate cancer, urinary

MiR-145 detection in urinary extracellular vesicles increase diagnostic efficiency of prostate cancer based on hydrostatic filtration dialysis method.

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Abstract

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Bacterial extracellular vesicles

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