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      Vasodilators for Heart Failure - Useful or Useless?

      Cardiology

      S. Karger AG

      Vasodilators, Angiotensin-converting enzyme inhibitors, Heart failure, Heart function

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          Abstract

          Vasodilators have gained widespread acceptance in the management of congestive heart failure. They produce prompt hemodynamic and clinical improvement in acute left ventricular failure, and in chronic congestive heart failure they also improve symptoms, functional capacity, and survival. This efficacy, however, is limited to those vasodilators which have venodilating ability, such as nitrates and angiotensin-converting enzyme inhibitors, when they are added to digitalis and diuretics in patients with moderate to severe heart failure. The utility of vasodilators without digitalis or diuretics requires further evaluation. The potential for vasodilators to prevent the development or progression of heart failure from latent to clinically overt disease is also being evaluated.

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          Author and article information

          Journal
          CRD
          Cardiology
          10.1159/issn.0008-6312
          Cardiology
          S. Karger AG
          978-3-8055-4929-5
          978-3-318-01863-9
          0008-6312
          1421-9751
          1988
          1988
          11 November 2008
          : 75
          : Suppl 1
          : 110-117
          Affiliations
          Cardiovascular Section, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pa., and Clinical Research Department, ICI Pharmaceuticals Group, ICI Americas Inc., Wilmington, Del., USA
          Article
          174450 Cardiology 1988;75:110–117
          10.1159/000174450
          3069208
          © 1988 S. Karger AG, Basel

          Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

          Page count
          Pages: 8
          Categories
          Session III

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