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      Pheno-phenotypes: a holistic approach to the psychopathology of schizophrenia.

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      Current opinion in psychiatry

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          Abstract

          Mental disorders are mainly characterized via symptom assessment. Symptoms are state-like macroscopic anomalies of behaviour, experience, and expression that are deemed relevant for diagnostic purposes. An alternative approach is based on the concept of endophenotypes, which are physiological or behavioural measures occupying the terrain between symptoms and risk genotypes. We will critically discuss these two approaches, and later focus on the concept of pheno-phenotype as it is revealed by recent phenomenological research on schizophrenia.

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          Author and article information

          Journal
          Curr Opin Psychiatry
          Current opinion in psychiatry
          1473-6578
          0951-7367
          May 2014
          : 27
          : 3
          Affiliations
          [1 ] aG. d'Annunzio University, Chieti, Italy bD. Portales University, Santiago University, Chile cLaboratory of Molecular Psychiatry and Psychopharmacotherapeutics, Section of Psychiatry, Department of Neuroscience, University School of Medicine Federico II, Naples, Italy.
          Article
          10.1097/YCO.0000000000000059
          24613980

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