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      Arrhythmogenic Right Ventricular Dysplasia: A Review

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          Abstract

          Arrhythmogenic right ventricular (RV) dysplasia is a predominant disorder of the RV, characterized by progressive replacement of myocardium by fibroadipose tissue and arrhythmic manifestations. It remains incompletely known despite the fact that it may cause sudden death, often exertional, in young and healthy individuals. The etiology is speculative and the disorder has autosomal dominant genetic predisposition. Commonly, the physical examination is unremarkable and the commonest abnormality on routine ECG is inverted T-waves on precordial leads. Morphologic abnormality of dysplastic RV can be detected by echocardiogram, radionuclear angiogram or contrast RV angiogram. They may miss cases with less involvement where gated MRI scans may be useful. Patients with syncope or symptomatic ventricular tachycardia have worse prognosis. Pharmacologic antiarrhythmic therapy is sometimes disappointing and various surgical and endocardial ablation procedures have been tried with varying success.

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          Author and article information

          Journal
          CRD
          Cardiology
          10.1159/issn.0008-6312
          Cardiology
          S. Karger AG
          0008-6312
          1421-9751
          1994
          1994
          18 November 2008
          : 85
          : 6
          : 361-369
          Affiliations
          aDepartment of Cardiology, bDepartment of Medicine and Arrhythmia Service, Beth Israel Medical Center, New York, N.Y., USA
          Article
          176737 Cardiology 1994;85:361–369
          10.1159/000176737
          7697671
          © 1994 S. Karger AG, Basel

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          Page count
          Pages: 9
          Categories
          Review

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