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      Mental Stress and Ventricular Arrhythmias.

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          Abstract

          Anger and other negative emotions can precipitate sudden death, as shown in studies of population stressors. Clinical studies of patients with implantable defibrillators demonstrate that anger can trigger ventricular arrhythmias. Long-term negative emotions also increase vulnerability to arrhythmias. Mechanisms linking anger and arrhythmias include autonomic changes, which alter repolarization, possibly enhanced in patients with sympathetic denervation, which in turn trigger potentially lethal polymorphic ventricular tachycardias. Interventions which decrease negative emotions and resultant autonomic responses may be therapeutic in patients with implantable cardioverter defibrillators.

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          Author and article information

          Journal
          Curr Cardiol Rep
          Current cardiology reports
          Springer Nature America, Inc
          1534-3170
          1523-3782
          December 2016
          : 18
          : 12
          Affiliations
          [1 ] Yale University School of Medicine, Cardiovascular Medicine, 789 Howard Avenue, Dana 319, 06520, New Haven, CT, USA. rachel.lampert@yale.edu.
          Article
          10.1007/s11886-016-0798-6
          10.1007/s11886-016-0798-6
          27796855
          00e9e2c0-59ee-44c0-b21f-2ae713d86470

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