+1 Recommend
1 collections
      • Record: found
      • Abstract: found
      • Article: found

      Elevated Divalent Ion Concentrations in Parotid Saliva from Chronic Renal Failure Patients



      S. Karger AG

      Chronic renal failure, Parotid gland, Secretion

      Read this article at

          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.


          Mg and PO<sub>4</sub> concentrations were significantly higher in unmixed parotid saliva from chronic renal failure (CRF) patients than in controls. No significant differences were noted in the flow, pH or concentrations of Na, K, Cl or Ca; however, the Na/K ratio was significantly lower in CRF patients. No correlation between plasma PTH levels and the concentrations of Ca, Mg, or PO<sub>4</sub> in saliva was found. Taken with previous results from elevated divalent ion concentrations in sweat from CRF patients, these findings suggest that the excretion of divalent electrolyte glands may represent a generalized abnormality in exocrine glands in CRF. We hypothesize that the active processes involved in regulating the concentrations of these ions in exocrine secretions are altered so that larger amounts of these elements are excreted in CRF patients.

          Related collections

          Author and article information

          S. Karger AG
          02 December 2008
          : 28
          : 2
          : 58-61
          Division of Nephrology, Departments of Medicine and Physiology, UCLA Medical School, Los Angeles, Calif., USA; Division of Biomedical Sciences, University of California, Riverside, Calif., USA
          182107 Nephron 1981;28:58–61
          © 1981 S. Karger AG, Basel

          Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

          Page count
          Pages: 4
          Original Paper

          Cardiovascular Medicine, Nephrology

          Chronic renal failure, Parotid gland, Secretion


          Comment on this article