17
views
0
recommends
+1 Recommend
0 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: not found

      Immediate therapeutic efficacy of low-density lipoprotein apheresis for drug-resistant nephrotic syndrome: evidence from the short-term results from the POLARIS Study.

      Read this article at

      ScienceOpenPublisherPubMed
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Hyperlipidemia is not merely a complication but a major exacerbating factor in longstanding nephrotic syndrome (NS). Low-density lipoprotein apheresis (LDL-A) has been reported to ameliorate dyslipidemia and induce rapid remission of NS. Several clinical studies have suggested the therapeutic efficacy of LDL-A, but the level of clinical evidence is insufficient. Therefore, a multicenter prospective study, POLARIS (Prospective Observational Survey on the Long-Term Effects of LDL Apheresis on Drug-Resistant Nephrotic Syndrome), was initiated in Japan.

          Related collections

          Author and article information

          Journal
          Clin. Exp. Nephrol.
          Clinical and experimental nephrology
          Springer Nature
          1437-7799
          1342-1751
          Jun 2015
          : 19
          : 3
          Affiliations
          [1 ] Division of Nephrology and Dialysis, Kitano Hospital, Tazuke Kofukai Medical Institute, 2-4-20 Ohgimachi, Kita-ku, Osaka, 530-8480, Japan. muso@kitano-hp.or.jp.
          [2 ] Ryoshukai Takaishi Fujii Hospital, Takaishi, Japan.
          [3 ] Department of Diabetes, Metabolism, and Endocrinology, Showa University School of Medicine, Tokyo, Japan.
          [4 ] Department of Pediatric Nephrology, Tokyo Women's Medical University, Tokyo, Japan.
          [5 ] Department of Nephrology and Hypertension, Internal Medicine, St. Marianna University School of Medicine, Kawasaki, Japan.
          [6 ] Department of Nephrology, Hypertension, Diabetology, Endocrinology and Metabolism, Fukushima Medical University School of Medicine, Fukushima, Japan.
          [7 ] Division of Nephrology, Kanazawa Medical University School of Medicine, Uchinada, Japan.
          [8 ] Department of Clinical Pharmacology and Therapeutics, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Japan.
          [9 ] Department of Internal Medicine, Teikyo University School of Medicine, Tokyo, Japan.
          [10 ] Department of Laboratory Medicine, Kanazawa University Graduate School of Medicine, Kanazawa, Japan.
          [11 ] Department of Metabolism, Endocrinology and Molecular Medicine, Osaka City University Graduate School of Medicine, Osaka, Japan.
          [12 ] Department of Nephrology, Fujita Health University School of Medicine, Toyoake, Japan.
          [13 ] Department of Pediatrics, Kinki University School of Medicine, Osaka-Sayama, Japan.
          [14 ] Division of Nephrology, Kanayama Clinic, Nagoya, Japan.
          [15 ] Division of Nephrology and Rheumatology, Department of Internal Medicine, Fukuoka University, Fukuoka, Japan.
          [16 ] Department of Advanced Nephrology, Graduate School of Biomedical Science, Hiroshima University, Hiroshima, Japan.
          [17 ] The Kidney Foundation, Japan, Tokyo, Japan.
          [18 ] Wakayama KD Clinic, Wakayama, Japan.
          [19 ] Department of Nephrology, Nippon Medical School, Tokyo, Japan.
          [20 ] Nakayamadera Imai Clinic, Takarazuka, Japan.
          [21 ] Department of Nephrology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
          [22 ] Faculty of Medicine, General Medical Research Center, Fukuoka University, Fukuoka, Japan.
          Article
          10.1007/s10157-014-0996-8
          10.1007/s10157-014-0996-8
          24934117
          017e3c82-acd2-41b7-b08a-328810a99538
          History

          Drug-resistant nephrotic syndrome,LDL apheresis,Lipid nephrotoxicity,Short-term results

          Comments

          Comment on this article