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      Efficacy and safety of multifocal intraocular lenses following cataract and refractive lens exchange: Metaanalysis of peer-reviewed publications.

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          Abstract

          We performed a metaanaysis of peer-reviewed studies involving implantation of a multifocal intraocular lens (IOL) in presbyopic patients with cataract or having refractive lens exchange (RLE). Previous reviews have considered the use of multifocal IOLs after cataract surgery but not after RLE, whereas greater insight might be gained from examining the full range of studies. Selected studies were examined to collate outcomes with monocular and binocular uncorrected distance, intermediate, and near visual acuity; spectacle independence; contrast sensitivity; visual symptoms; adverse events; and patient satisfaction. In 8797 eyes, the mean postoperative monocular uncorrected distance visual acuity (UDVA) was 0.05 logMAR ± 0.006 (SD) (Snellen equivalent 20/20(-3)). In 6334 patients, the mean binocular UDVA was 0.04 ± 0.00 logMAR (Snellen equivalent 20/20(-2)), with a mean spectacle independence of 80.1%. Monocular mean UDVA did not differ significantly between those who had a cataract procedure and those who had an RLE procedure. Neural adaptation to multifocality may vary among patients.

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          Author and article information

          Journal
          J Cataract Refract Surg
          Journal of cataract and refractive surgery
          Elsevier BV
          1873-4502
          0886-3350
          Feb 2016
          : 42
          : 2
          Affiliations
          [1 ] From a private practice (Rosen), Manchester, United Kingdom; the Division of Ophthalmology (Alió), Vissum Corporation, Universidad Miguel Hernandez, Alicante, Spain; the University Eye Hospital (Dick), Bochum, Germany; Dell Laser Consultants (Dell), Austin and Slade & Baker Vision (Slade), Houston, Texas, USA. Electronic address: erosen9850@aol.com.
          [2 ] From a private practice (Rosen), Manchester, United Kingdom; the Division of Ophthalmology (Alió), Vissum Corporation, Universidad Miguel Hernandez, Alicante, Spain; the University Eye Hospital (Dick), Bochum, Germany; Dell Laser Consultants (Dell), Austin and Slade & Baker Vision (Slade), Houston, Texas, USA.
          Article
          S0886-3350(16)00019-5
          10.1016/j.jcrs.2016.01.014
          27026457

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