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      Spectral-Domain Optical Coherence Tomography Angiography for the Diagnosis and Evaluation of Polypoidal Choroidal Vasculopathy

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          Abstract

          Purpose: To compare the diagnostic ability of optical coherence tomography angiography (OCTA) with indocyanine green angiography (ICGA) in polypoidal choroidal vasculopathy (PCV). Methods: Retrospective review of 47 eyes with PCV imaged with ICGA and OCTA. For each eye, it was determined which imaging modality better delineated the PCV complex. The presence of a branching vascular network (BVN) and polyp(s) were noted. Results: PCV was better visualized with ICGA in 21 eyes (44.7%) and with OCTA in 9 eyes (19.2%). The results were comparable in 17 eyes (36.2%). Of the 44 eyes with BVN on ICGA, 41 eyes (93.2%) also showed BVN on OCTA. Of the 28 eyes with polyp(s) on ICGA, 22 eyes (78.6%) also showed polyp(s) on OCTA. Polyps were high-flow lesions or faint low-flow dilations on OCTA. Conclusion: OCTA readily detects BVNs and can detect most polyps, but in many cases ICGA is better able to detect the PCV complex.

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          Author and article information

          Journal
          OPH
          Ophthalmologica
          10.1159/issn.0030-3755
          Ophthalmologica
          S. Karger AG
          0030-3755
          1423-0267
          2018
          March 2018
          11 December 2017
          : 239
          : 2-3
          : 103-109
          Affiliations
          [_a] aUniversity of Hawaii Transitional Residency Program, Department of Medicine, University of Hawaii School of Medicine, Honolulu, Hawaii, USA
          [_b] bJohn A. Burns School of Medicine, University of Hawaii School of Medicine, Honolulu, Hawaii, USA
          [_c] cThe Retina Center at Pali Momi, Aiea, Hawaii, USA
          [_d] dRetina Consultants of Hawaii, Honolulu, Hawaii, USA
          [_e] eHawaii Macula and Retina Institute, Aiea, Hawaii, USA
          [_f] fDivision of Ophthalmology, Department of Surgery, University of Hawaii School of Medicine, Honolulu, Hawaii, USA
          Author notes
          *Gregg T. Kokame, MD, Retina Consultants of Hawaii, 98-1079 Moanalua Road, Suite 470, Aiea, HI 96701 (USA), E-Mail retinahi@aol.com
          Article
          481540 Ophthalmologica 2018;239:103–109
          10.1159/000481540
          29227980
          01ec3a71-546a-45b8-a5d7-f21b34e69efb
          © 2017 S. Karger AG, Basel

          Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

          History
          : 02 May 2017
          : 13 September 2017
          Page count
          Figures: 4, Tables: 1, Pages: 7
          Categories
          Research Paper

          Vision sciences,Ophthalmology & Optometry,Pathology
          Polypoidal choroidal vasculopathy,Optical coherence tomography,Indocyanine green angiography,Age-related macular degeneration

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