For Publishers
DiscoveryMetadataPeer reviewHostingPublishing
For Researchers
JoinPublishReviewCollect
Register
Blog
About
Search
Advanced search
My ScienceOpen
Search
For Publishers
For Researchers
Blog
About
38
views
8
references
 Top references
cited by
126
    
0 reviews
 Review
0
comments
 Comment
0
recommends
+1 Recommend
1 collections
    0
    shares
      516
      similar
       All similar
      • Record: found
      • Abstract: found
      • Article: not found

      Audiological profile of asymptomatic Covid-19 PCR-positive cases

      research-article
      Author(s):
      Publication date (Electronic):
      Journal: American Journal of Otolaryngology
      Publisher: Elsevier Inc.
      Keywords: COVID-19, Corona virus, Hearing loss, Cochlear function

      Read this article at

      ScienceOpenPublisherPMC
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Objective

          The current study compared the amplitude of transient evoked otoacoustic emissions (TEOAEs) and latencies of vestibular evoked myogenic potentials (VEMPs) between asymptomatic COVID-19 PCR-positive cases and normal non-infected subjects.

          Methods

          Twenty cases who were confirmed positive for COVID-19 and had none of the known symptoms for this viral infection formed the test group for 2 full weeks. Their age ranged between 20 and 50 years to avoid any age-related hearing affection. Patients who had definite symptoms of COVID-19 infection as well as those who had a history of hearing loss or a history of any known cause of hearing loss were excluded from the examined sample. TEOAEs amplitude was measured for all participants.

          Results

          The high frequency pure-tone thresholds as well as the TEOAE amplitudes were significantly worse in the test group.

          Conclusions

          COVID-19 infection could have deleterious effects on cochlear hair cell functions despite being asymptomatic. The mechanism of these effects requires further research.

          Related collections

          Most cited references8

          • Record: found
          • Abstract: found
          • Article: found
          Is Open Access

          The origin, transmission and clinical therapies on coronavirus disease 2019 (COVID-19) outbreak – an update on the status

          Yan-Rong Guo, Qing-Dong Cao, Zhong-Si Hong … (2020)
          An acute respiratory disease, caused by a novel coronavirus (SARS-CoV-2, previously known as 2019-nCoV), the coronavirus disease 2019 (COVID-19) has spread throughout China and received worldwide attention. On 30 January 2020, World Health Organization (WHO) officially declared the COVID-19 epidemic as a public health emergency of international concern. The emergence of SARS-CoV-2, since the severe acute respiratory syndrome coronavirus (SARS-CoV) in 2002 and Middle East respiratory syndrome coronavirus (MERS-CoV) in 2012, marked the third introduction of a highly pathogenic and large-scale epidemic coronavirus into the human population in the twenty-first century. As of 1 March 2020, a total of 87,137 confirmed cases globally, 79,968 confirmed in China and 7169 outside of China, with 2977 deaths (3.4%) had been reported by WHO. Meanwhile, several independent research groups have identified that SARS-CoV-2 belongs to β-coronavirus, with highly identical genome to bat coronavirus, pointing to bat as the natural host. The novel coronavirus uses the same receptor, angiotensin-converting enzyme 2 (ACE2) as that for SARS-CoV, and mainly spreads through the respiratory tract. Importantly, increasingly evidence showed sustained human-to-human transmission, along with many exported cases across the globe. The clinical symptoms of COVID-19 patients include fever, cough, fatigue and a small population of patients appeared gastrointestinal infection symptoms. The elderly and people with underlying diseases are susceptible to infection and prone to serious outcomes, which may be associated with acute respiratory distress syndrome (ARDS) and cytokine storm. Currently, there are few specific antiviral strategies, but several potent candidates of antivirals and repurposed drugs are under urgent investigation. In this review, we summarized the latest research progress of the epidemiology, pathogenesis, and clinical characteristics of COVID-19, and discussed the current treatment and scientific advancements to combat the epidemic novel coronavirus.
          Article 0 comments Cited 1671 times – based on 0 reviews     Review now
            • Record: found
            • Abstract: not found
            • Article: not found

            Preferred Method For Clinical Determination Of Pure-Tone Thresholds

            Raymond Carhart, James Jerger (1959)
            Article 0 comments Cited 144 times – based on 0 reviews     Review now
              • Record: found
              • Abstract: not found
              • Article: not found

              Congenital cytomegalovirus screening.

              Stuart Adler (2005)
              Article 0 comments Cited 19 times – based on 0 reviews     Review now
                All references

                Author and article information

                Contributors
                M.W.M. Mustafa
                Journal
                Journal ID (nlm-ta): Am J Otolaryngol
                Journal ID (iso-abbrev): Am J Otolaryngol
                Title: American Journal of Otolaryngology
                Publisher: Elsevier Inc.
                ISSN (Print): 0196-0709
                ISSN (Electronic): 1532-818X
                Publication date PMC-release: 10 April 2020
                Publication date (Electronic): 10 April 2020
                Electronic Location Identifier: 102483
                Affiliations
                Otorhinolaryngology Department, Qena Faculty of Medicine, South Valley University, Qena 83532, Egypt
                Article
                Publisher ID: S0196-0709(20)30165-4 Publisher ID: 102483
                DOI: 10.1016/j.amjoto.2020.102483
                PMC ID: 7151386
                PubMed ID: 32307189
                SO-VID: 01ef055b-fb0f-465c-bd9a-d004f4d4fcf9
                Copyright © © 2020 Elsevier Inc. All rights reserved.
                License:

                Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.

                History
                Date received : 6 April 2020
                Categories
                Subject: Article

                Keywords: covid-19,corona virus,hearing loss,cochlear function
                Data availability:
                Keywords: covid-19, corona virus, hearing loss, cochlear function

                Comments

                Comment on this article

                Related Documents Log
                scite_

                Similar content516

                See all similar

                Cited by125

                See all cited by

                Most referenced authors213

                See all reference authors