CDX2 and LEF-1 expression in pilomatrical tumors and their utility in the diagnosis of pilomatrical carcinoma.

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Abstract

The Wnt signaling pathway has been implicated in the pathogenesis of pilomatrical tumors. Lymphoid enhancer-binding factor 1 (LEF-1) is a downstream component of this pathway, and Caudal-related homeobox transcription factor 2 (CDX2) has been postulated to regulate it, but little is known about expression of these transcription factors in pilomatrical tumors.

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Author and article information

Journal

Journal ID (iso-abbrev): J Cutan Pathol

Title: Journal of cutaneous pathology

Publisher: Wiley

ISSN (Electronic): 1600-0560

ISSN (Print): 0303-6987

Publication date (Electronic): May 2018

Volume: 45

Issue: 5

Affiliations

[1 ] University of Mississippi Medical Center, Department of Pathology, Jackson, Mississippi.

[2 ] ProPath, Division of Dermatopathology, Dallas, Texas.

[3 ] University of Texas Southwestern Medical Center, Department of Dermatology, Dallas, Texas.

[4 ] University of Texas Southwestern Medical Center, Department and Pathology, Dallas, Texas.

Article

DOI: 10.1111/cup.13113

PubMed ID: 29369390

SO-VID: 0226b93f-d11e-4c58-89c9-365281285829

History

Keywords: CDX2,LEF-1,pilomatrical carcinoma,pilomatricoma

Data availability:

Keywords: CDX2, LEF-1, pilomatrical carcinoma, pilomatricoma

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