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      Pulmonary toxicity among cancer patients treated with a combination of docetaxel and gemcitabine: a meta-analysis of clinical trials.

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          Abstract

          The combination of docetaxel and gemcitabine was tested in several studies in patients with lung, breast, and pancreatic cancers and other tumor entities. Some studies reported cases of severe or even fatal pulmonary toxicity that led to early termination of some trials. We created a meta-analysis model of published studies to identify explanatory factors for docetaxel-gemcitabine-dependent pulmonary toxicity.

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          Author and article information

          Journal
          Cancer Chemother. Pharmacol.
          Cancer chemotherapy and pharmacology
          Springer Nature
          1432-0843
          0344-5704
          Dec 2011
          : 68
          : 6
          Affiliations
          [1 ] Department of Internal Medicine/Infectious and Respiratory Diseases, Charité-Universitätsmedizin Berlin, Berlin, Germany. daniel.binder@charite.de
          Article
          10.1007/s00280-011-1648-2
          21547571
          023d93b9-d7fe-47b8-a5df-cf1e9323d676
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