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      Catecholamines Induce Trained Immunity in Monocytes In Vitro and In Vivo.

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          Abstract

          Exposure to high catecholamine levels is associated with inflammatory changes of myeloid cells and atherosclerosis, but the underlying mechanisms are only partly understood.

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          Author and article information

          Journal
          Journal ID (iso-abbrev): Circ. Res.
          Title: Circulation research
          Publisher: Ovid Technologies (Wolters Kluwer Health)
          ISSN (Electronic): 1524-4571
          ISSN (Print): 0009-7330
          Publication date (Electronic): Jul 03 2020
          Volume: 127
          Issue: 2
          Affiliations
          [1 ] From the Department of Internal Medicine (C.D.C.C.v.d.H., L.G., S.T.K., M.P.N., S.K., A.H., L.A.B.J., H.J.L.M.T., M.G.N., N.P.R.), Radboud University Medical Center, Nijmegen, the Netherlands.
          [2 ] Radboud Institute of Molecular Life Sciences (C.D.C.C.v.d.H., L.G., S.T.K., M.P.N., S.K., A.H., L.A.B.J., M.G.N., N.P.R.), Radboud University Medical Center, Nijmegen, the Netherlands.
          [3 ] Department of Human Genetics (S.K., A.H.), Radboud University Medical Center, Nijmegen, the Netherlands.
          [4 ] Centre for Molecular and Biomolecular Informatics, Radboud Institute for Molecular Life Sciences (C.K.), Radboud University Medical Center, Nijmegen, the Netherlands.
          [5 ] Department of Laboratory Medicine (A.E.v.H.), Radboud University Medical Center, Nijmegen, the Netherlands.
          [6 ] Department of Medical Genetics, Iµliu Hațieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania (L.A.B.J.).
          [7 ] Department for Genomics and Immunoregulation, Life and Medical Sciences 12 Institute, University of Bonn, Germany (M.G.N.).
          Article
          DOI: 10.1161/CIRCRESAHA.119.315800
          PubMed ID: 32241223
          SO-VID: 02763abc-4f61-4ed9-9f18-e7dbc15d7cd9
          History

          Keywords: pheochromocytoma,norepinephrine,innate immune system,inflammation,epinephrine,catecholamines
          Data availability:
          Keywords: pheochromocytoma, norepinephrine, innate immune system, inflammation, epinephrine, catecholamines

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