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      Rabdomiólisis recurrente en un niño: Presentación de un caso Translated title: Recurrent rhabdomyolysis in a child: Case presentation

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          Abstract

          La miositis viral asociada a infecciones raramente produce rabdomiólisis. En las publicaciones científicas no se describe ningún caso pediátrico de rabdomiólisis grave recurrente inducida por infecciones. En este artículo presentamos el caso de un niño de sexo masculino de dos años de edad hospitalizado en tres ocasiones debido a rabdomiólisis grave asociada a miositis viral durante el invierno. Esta es la primera presentación de un caso pediátrico de rabdomiólisis grave inducida por infecciones. En este paciente, el tratamiento con prednisolona e inmunoglobulinas por vía i.v. fue ineficaz.

          Translated abstract

          Viral myositis associated with infections rarely may cause rhabdomyolysis. There is no any pediatric case with severe recurrent rhabdomyolysis triggered by infections in the literature. We reported a two-year-old boy who was hospitalized three times due to severe rhabdomyolysis associated with viral myositis in the winter months. This is the first child case presentation with severe rhabdomyolysis triggered by infections. Prednisolone and intravenous immunoglobulin treatments were ineffective in this case.

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          Most cited references12

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          Acute pediatric rhabdomyolysis: causes and rates of renal failure.

          The goals were to (1) compare the causes, clinical presentation, and prevalence of acute renal failure in pediatric rhabdomyolysis with the published data for adults; (2) determine predictors of acute renal failure in pediatric patients with rhabdomyolysis; and (3) explore the relationship of acute renal failure with treatment modalities such as fluid and bicarbonate administration. We performed a retrospective chart review to identify patients with creatinine kinase levels of > 1000 IU/L who were treated in the emergency department of a tertiary pediatric hospital between 1993 and 2003, and we constructed regression models. Two hundred ten patients were studied. One hundred ninety-one patients met study eligibility (128 male and 63 female), with a median age of 11 years. The most common documented symptoms were muscle pain (45%), fever (40%), and symptoms of viral infection (39%). The most common causes of pediatric rhabdomyolysis were viral myositis (38%), trauma (26%), and connective tissue disease (5%). Six of 37 patients with creatinine kinase levels of > or = 6000 IU/L had previously undiagnosed dermatomyositis or hereditary metabolic disease, compared with 10 of 154 patients with creatinine kinase levels of 1000 to 5999 IU/L. Nine of 191 patients developed acute renal failure. None of 99 patients with initial urinary heme dipstick results of or = 2+. Higher initial creatinine kinase levels and higher fluid administration rates were associated with higher maximal creatinine levels. The cause of acute pediatric rhabdomyolysis is different from that of adult rhabdomyolysis. The risk of acute renal failure in children is much less than the risk reported for adults.
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            Clinical features of influenza A and B in children and association with myositis.

            Influenza virus is among the most common causes of respiratory illness, which may manifest as a range of conditions, from mild upper respiratory tract infection to bronchiolitis and pneumonia. Acute childhood myositis associated with influenza occurs mostly in influenza B infection. In this retrospective study, we analyzed the characteristics of 197 children with influenza virus treated from January 2000 to December 2001. Among them, 73 children had influenza A infection and 124 had influenza B infection. Influenza A virus outbreaks occurred in January 2000, July 2001, and December 2001, while influenza B virus outbreaks occurred from March 2000 to May 2000 and from December 2000 to February 2001. The most common clinical manifestations of influenza A and influenza B virus infection included fever, cough, and rhinorrhea. These infections also frequently manifested as laryngo-tracheobronchitis, pneumonia, and unexplained fever, which led to hospitalization. The most common clinical diagnosis was upper respiratory tract infection. The rates of benign acute childhood myositis in influenza A and influenza B were 5.5% and 33.9%, respectively. Creatine kinase levels were elevated in most myositis cases and boys were more commonly affected. Acute childhood myositis was more commonly seen in influenza B infection.
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              Biochemical investigation of suspected rhabdomyolysis.

              R Beetham (2000)
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                Author and article information

                Contributors
                Role: ND
                Role: ND
                Role: ND
                Role: ND
                Role: ND
                Journal
                aap
                Archivos argentinos de pediatría
                Arch. argent. pediatr.
                Sociedad Argentina de Pediatría (Buenos Aires, , Argentina )
                0325-0075
                1668-3501
                June 2016
                : 114
                : 3
                : e191-e194
                Affiliations
                [03] Diyarbakir orgnameDicle University orgdiv1Facultad de Medicina orgdiv2Departamento de Enfermedades Infecciosas y Microbiología Clínica Turquía
                [01] Diyarbakir orgnameDicle University orgdiv1Facultad de Medicina orgdiv2Departamento de Pediatría Turquía
                [02] Diyarbakir orgnameHospital Pediátrico de Diyarbakir orgdiv1Departamento de Pediatría Turquía
                Article
                S0325-00752016000300027
                10.5546/aap.2016.e192
                02923120-23f9-4c88-bfd7-7b54d8656f6e

                This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

                History
                : 19 October 2015
                : 14 December 2015
                Page count
                Figures: 0, Tables: 0, Equations: 0, References: 12, Pages: 0
                Product

                SciELO Argentina


                Rabdomiólisis aguda grave,Infección,Virus sincicial respiratorio,Pediatría,Rhabdomyolysis acute recurrent,Infection,Respiratory syncytial virus,Pediatrics

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