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      Evaluation of Disk Halo Size after Implantation of a Collamer Lens with a Central Hole (ICL V4c)

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          Abstract

          Purpose

          To investigate disk halo size changes produced by a glare source after surgical insertion of an implantable collamer lens with a central hole (ICL V4c) for myopia correction.

          Methods

          In this prospective study, disk halo size and pupillary light response with a vision monitor were measured preoperatively and at 1 week, 1 month, and 3 months postoperatively. Pupillary light response parameters included contraction amplitude, latency, duration, and velocity; dilation latency, duration, and velocity; and initial, maximum, minimum, and average pupil diameters.

          Results

          Forty-two right eyes of 42 patients were enrolled. Postoperative uncorrected distance visual acuity was better than or equal to 20/20 in all eyes. Compared to preoperative values, disk halo size showed no significant difference at 1 week postoperatively ( P > 0.05) and then decreased significantly at 1 and 3 months postoperatively (both P < 0.001). Contraction amplitude and velocity, as well as dilation velocity, decreased significantly at all postoperative time points (all P < 0.001). Disk halo size at 3 months postoperatively was significantly correlated with initial ( r = 0.446, P=0.003), maximum ( r = 0.483, P=0.001), minimum ( r = 0.425, P=0.005), and average pupil diameters ( r = 0.474, P=0.002).

          Conclusions

          After ICL V4c implantation, disk halo size was reduced in the short term. Patients with smaller pupil sizes during pupillary response to light experienced smaller halos after ICL V4c implantation.

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          Most cited references24

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          Posterior chamber phakic intraocular lens implantation: comparative, multicentre study in 351 eyes with low-to-moderate or high myopia

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            Intraindividual comparison of visual performance after posterior chamber phakic intraocular lens with and without a central hole implantation for moderate to high myopia.

            To compare postoperative visual performance after implantable Collamer lenses with and without a central hole (Hole ICL and conventional ICL) are implanted to correct moderate to high myopia.
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              The Effects of Age, Refractive Status, and Luminance on Pupil Size

              ABSTRACT Purpose Pupil size is critical for optimal performance of presbyopic contact lenses. Although the effect of luminance is well known, little information is available regarding other contributing factors such as aging and refractive status. Methods The cohort population comprised 304 patients (127 male, 177 female) aged 18 to 78 years. Pupils were photographed at three controlled luminance levels 250, 50, and 2.5 cd/m2 using an infra-red macro video camera. Measurements of pupil diameter were conducted after transforming pixel values to linear values in millimeters. Results Luminance was the most influential factor with pupil diameter increasing with decreased luminance (p < 0.001, all comparisons). Age was also found to be a significant factor with a smaller diameter in the older groups, but overall the difference was only significant between the pre-presbyopes and the established presbyopes (p = 0.017). Pupil diameter decreased significantly with increasing age, the effect being most marked at low luminance (<0.001). The smallest pupil diameters were measured for hyperopes and the largest for myopes and although refractive error was not a significant factor alone, there was a significant interaction between luminance and refractive error with the greatest differences in pupil diameter between myopes and emmetropes at low luminance (p < 0.001). Pupil diameter changes modeled by multilinear regression (p < 0.001) identified age, luminance, best sphere refraction, and refractive error as significant factors accounting for just over 70% of the average variation in pupil diameter. Conclusions Both age and refractive status were found to affect pupil size with larger pupils measured for younger patients and myopes. Designs for multifocal contact lens corrections should take both age and refractive status into consideration; a faster progression from distance to near corrections across the optical zone of the lens is expected to be required for established presbyopes and hyperopes than it is for early presbyopes, myopes, and emmetropes.
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                Author and article information

                Contributors
                Journal
                J Ophthalmol
                J Ophthalmol
                JOPH
                Journal of Ophthalmology
                Hindawi
                2090-004X
                2090-0058
                2019
                14 August 2019
                : 2019
                : 7174913
                Affiliations
                1Department of Ophthalmology, Eye and ENT Hospital of Fudan University, Shanghai, China
                2NHC Key Laboratory of Myopia (Fudan University), Shanghai, China
                3Research Center of Ophthalmology and Optometry Shanghai, Shanghai, China
                4The Department of Ophthalmology, Shuguang Hospital of Shanghai University of Traditional Chinese Medicine, Shanghai, China
                Author notes

                Academic Editor: Anna Nowinska

                Author information
                https://orcid.org/0000-0001-5419-6318
                https://orcid.org/0000-0002-3465-1579
                Article
                10.1155/2019/7174913
                6710753
                31485347
                02a60948-7fff-46bb-8f10-f82d570f39a6
                Copyright © 2019 Xun Chen et al.

                This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

                History
                : 9 April 2019
                : 11 July 2019
                Funding
                Funded by: National Natural Science Foundation of China
                Award ID: 81600762
                Award ID: 81700872
                Award ID: 81570879
                Award ID: 81770955
                Funded by: Project of Shanghai Science and Technology
                Award ID: 19140900700
                Award ID: 17140902900
                Award ID: 17411950200
                Award ID: 17411950201
                Funded by: Shanghai Shenkang Hospital Development Center
                Award ID: SHDC12016207
                Categories
                Clinical Study

                Ophthalmology & Optometry
                Ophthalmology & Optometry

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