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Biophysical characterization of MDR breast cancer cell lines reveals the cytoplasm is critical in determining drug sensitivity.
H M Coley, Hilary Llewellyn-Thomas, Dennis P M Hughes, Fatima Labeed
2007-03-31
metabolism, Anthracyclines, Antineoplastic Agents, pharmacology, Breast Neoplasms, pathology, Carbocyanines, Cell Line, Tumor, Cell Survival, drug effects, Cisplatin, Colchicine, Cytoplasm, Doxorubicin, Drug Resistance, Multiple, Phenotype, Drug Resistance, Neoplasm, Electrophoresis, methods, Etoposide, Female, Fluorescent Dyes, Humans, Inhibitory Concentration 50, Membrane Potentials, Membrane Transport Proteins, Multidrug Resistance-Associated Proteins, Neoplasm Proteins, P-Glycoprotein, Paclitaxel, ATP-Binding Cassette Transporters
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17270349
10.1016/j.bbagen.2006.12.002
metabolism, Anthracyclines, Antineoplastic Agents, pharmacology, Breast Neoplasms, pathology, Carbocyanines, Cell Line, Tumor, Cell Survival, drug effects, Cisplatin, Colchicine, Cytoplasm, Doxorubicin, Drug Resistance, Multiple, Phenotype, Drug Resistance, Neoplasm, Electrophoresis, methods, Etoposide, Female, Fluorescent Dyes, Humans, Inhibitory Concentration 50, Membrane Potentials, Membrane Transport Proteins, Multidrug Resistance-Associated Proteins, Neoplasm Proteins, P-Glycoprotein, Paclitaxel, ATP-Binding Cassette Transporters