Melilotus albus Medik. is a cosmopolite and invasive species, native to the Old World, which in Brazil had its occurrence hitherto recorded only in the states of São Paulo, Paraná and Rio Grande do Sul. This study extends its distribution to Santa Catarina state, southern Brazil, due to the recent discovery of populations in the municipalities of Florianópolis and Xanxerê. These new records are ca. 250 km distant from the nearest records, in Paraná state, also in southern Brazil.