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      Thrombolytic Therapy of a Stenosed Coronary Vein Bypass Graft with Continuous Intragraft Streptokinase Drip

      , , ,

      Cardiology

      S. Karger AG

      Fibrinolysis, Graft occlusion, Saphenous vein

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          Abstract

          A patient with newly onset angina due to recent thrombotic occlusion of a saphenous vein graft to the left anterior descending coronary artery is described. The patient was successfully treated by a direct intragraft infusion of streptokinase (STK) followed by a continuous intragraft infusion of an additional 1.5 million units of STK during the next 20 h through a regular diagnostic catheter. The patient was discharged on oral anticoagulant treatment with remarkable relief of the angina. Repeat angiography showed complete dissolution of the graft thrombus. This patient demonstrates that continuous infusion of STK into a saphenous vein graft is an effective treatment for recently formed thrombi.

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          Author and article information

          Journal
          CRD
          Cardiology
          10.1159/issn.0008-6312
          Cardiology
          S. Karger AG
          0008-6312
          1421-9751
          1990
          1990
          12 November 2008
          : 77
          : 4
          : 318-321
          Affiliations
          Cardiac Department, Hadassah University Hospital, Jerusalem, Israel
          Article
          174615 Cardiology 1990;77:318–321
          10.1159/000174615
          2073649
          © 1990 S. Karger AG, Basel

          Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

          Page count
          Pages: 4
          Categories
          Case Reports

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