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      Contextualising Maximal Fat Oxidation During Exercise: Determinants and Normative Values

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          Abstract

          Using a short-duration step protocol and continuous indirect calorimetry, whole-body rates of fat and carbohydrate oxidation can be estimated across a range of exercise workloads, along with the individual maximal rate of fat oxidation (MFO) and the exercise intensity at which MFO occurs (Fat max). These variables appear to have implications both in sport and health contexts. After discussion of the key determinants of MFO and Fat max that must be considered during laboratory measurement, the present review sought to synthesize existing data in order to contextualize individually measured fat oxidation values. Data collected in homogenous cohorts on cycle ergometers after an overnight fast was synthesized to produce normative values in given subject populations. These normative values might be used to contextualize individual measurements and define research cohorts according their capacity for fat oxidation during exercise. Pertinent directions for future research were identified.

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          Most cited references135

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          Short-term sprint interval versus traditional endurance training: similar initial adaptations in human skeletal muscle and exercise performance.

          Brief, intense exercise training may induce metabolic and performance adaptations comparable to traditional endurance training. However, no study has directly compared these diverse training strategies in a standardized manner. We therefore examined changes in exercise capacity and molecular and cellular adaptations in skeletal muscle after low volume sprint-interval training (SIT) and high volume endurance training (ET). Sixteen active men (21 +/- 1 years, ) were assigned to a SIT or ET group (n = 8 each) and performed six training sessions over 14 days. Each session consisted of either four to six repeats of 30 s 'all out' cycling at approximately 250% with 4 min recovery (SIT) or 90-120 min continuous cycling at approximately 65% (ET). Training time commitment over 2 weeks was approximately 2.5 h for SIT and approximately 10.5 h for ET, and total training volume was approximately 90% lower for SIT versus ET ( approximately 630 versus approximately 6500 kJ). Training decreased the time required to complete 50 and 750 kJ cycling time trials, with no difference between groups (main effects, P
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              Impact of Cardiorespiratory Fitness on All-Cause and Disease-Specific Mortality: Advances Since 2009

              Cardiorespiratory fitness (CRF) has been one of the most widely examined physiological variables, particularly as it relates to functional capacity and human performance. Over the past three decades, CRF has emerged as a strong, independent predictor of all-cause and disease-specific mortality. The evidence supporting the prognostic use of CRF is so powerful that the American Heart Association recently advocated for the routine assessment of CRF as a clinical vital sign. Interestingly, the continuity of evidence of the inverse relationship between CRF and mortality over the past decade exists despite a wide variation of methods used to assess CRF in these studies, ranging from the gold-standard method of directly measured maximal oxygen uptake (VO2max) during cardiopulmonary exercise testing to estimation from exercise tests and non-exercise prediction equations. This review highlights new knowledge and the primary advances since 2009, with specific reference to the impact variations in CRF have on all-cause and disease-specific mortality.
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                Author and article information

                Contributors
                Journal
                Front Physiol
                Front Physiol
                Front. Physiol.
                Frontiers in Physiology
                Frontiers Media S.A.
                1664-042X
                23 May 2018
                2018
                : 9
                : 599
                Affiliations
                Sports Performance Research Institute New Zealand, Auckland University of Technology , Auckland, New Zealand
                Author notes

                Edited by: Davide Malatesta, Université de Lausanne, Switzerland

                Reviewed by: Jean-Frédéric Brun, INSERM U1046 Physiologie et Médecine Expérimentale du Coeur et des Muscles, France; Todd Anthony Astorino, California State University San Marcos, United States

                *Correspondence: Ed Maunder ed.maunder@ 123456aut.ac.nz

                This article was submitted to Exercise Physiology, a section of the journal Frontiers in Physiology

                Article
                10.3389/fphys.2018.00599
                5974542
                29875697
                036fb09d-c57f-47f8-a070-7168c214c458
                Copyright © 2018 Maunder, Plews and Kilding.

                This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

                History
                : 26 February 2018
                : 03 May 2018
                Page count
                Figures: 2, Tables: 2, Equations: 0, References: 156, Pages: 13, Words: 12429
                Funding
                Funded by: Education New Zealand 10.13039/501100001550
                Categories
                Physiology
                Review

                Anatomy & Physiology
                fat oxidation,exercise,normative values,running,cycling
                Anatomy & Physiology
                fat oxidation, exercise, normative values, running, cycling

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