Contributors
Ohoud Subhi: Role: ConceptualizationRole: Formal analysisRole: InvestigationRole: MethodologyRole:
Writing – original draft
Hans-Juergen Schulten:
ORCID: http://orcid.org/0000-0002-4907-3222
Role: ConceptualizationRole: Data curationRole: Formal analysisRole: Funding acquisitionRole:
MethodologyRole: SupervisionRole: ValidationRole: Writing – original draftRole: Writing
– review & editing
Nadia Bagatian: Role: InvestigationRole: Methodology
Roa'a Al-Dayini: Role: InvestigationRole: Methodology
Sajjad Karim: Role: Data curationRole: Formal analysisRole: SoftwareRole: Supervision
Sherin Bakhashab:
ORCID: http://orcid.org/0000-0003-1580-0409
Role: ResourcesRole: Writing – original draft
Reem Alotibi: Role: InvestigationRole: Methodology
Alaa Al-Ahmadi: Role: InvestigationRole: Methodology
Manar Ata: Role: InvestigationRole: Methodology
Aisha Elaimi: Role: MethodologyRole: ResourcesRole: Supervision
Saad Al-Muhayawi: Role: Data curationRole: ResourcesRole: Supervision
Majid Mansouri: Role: Data curationRole: ResourcesRole: Supervision
Khalid Al-Ghamdi: Role: Data curationRole: InvestigationRole: Resources
Osman Abdel Hamour: Role: Data curationRole: ResourcesRole: Supervision
Awatif Jamal: Role: Data curationRole: InvestigationRole: Resources
Jaudah Al-Maghrabi: Role: Data curationRole: InvestigationRole: ResourcesRole: SupervisionRole: Writing
– review & editing
Mohammed Hussain Al-Qahtani: Role: Project administrationRole: ResourcesRole: SupervisionRole: Writing – review
& editing
Paula Soares: Role: Editor
Journal
Journal ID (nlm-ta): PLoS One
Journal ID (iso-abbrev): PLoS ONE
Journal ID (publisher-id): plos
Journal ID (pmc): plosone
Title:
PLoS ONE
Publisher:
Public Library of Science
(San Francisco, CA USA
)
ISSN
(Electronic):
1932-6203
Publication date
(Electronic):
30
June
2020
Publication date Collection: 2020
Volume: 15
Issue: 6
Electronic Location Identifier: e0234566
Affiliations
[1
]
Center of Excellence in Genomic Medicine Research, Department of Medical Laboratory
Technology, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah,
Saudi Arabia
[2
]
Department of Biochemistry, Faculty of Sciences, King Abdulaziz University, Jeddah,
Saudi Arabia
[3
]
Center of Innovation in Personalized Medicine, Department of Medical Laboratory Technology,
Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah, Saudi Arabia
[4
]
Department of Otolaryngology, Head and Neck Surgery, Faculty of Medicine, King Abdulaziz
University, Jeddah, Saudi Arabia
[5
]
Department of Surgery, King Faisal Specialist Hospital and Research Center, Jeddah,
Saudi Arabia
[6
]
Department of Pathology, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi
Arabia
[7
]
Department of Pathology, King Faisal Specialist Hospital and Research Center, Jeddah,
Saudi Arabia
Universidade do Porto Faculdade de Medicina, PORTUGAL
Author notes
Competing Interests: The authors have declared that no competing interests exist.
Author information
Article
Publisher ID:
PONE-D-19-35346
DOI: 10.1371/journal.pone.0234566
PMC ID: 7326236
PubMed ID: 32603365
SO-VID: 0392cb9d-a94a-4814-8f73-e0fa47ab890b
Copyright © © 2020 Subhi et al
License:
This is an open access article distributed under the terms of the
Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided
the original author and source are credited.
History
Date
received
: 20
December
2019
Date
accepted
: 28
May
2020
Page count
Figures: 7,
Tables: 1,
Pages: 21
Funding
HS (PI), AJ, KG, and JM (Co-Is) were supported by the National Plan for Science, Technology
and Innovation (MAARIFAH) – King Abdulaziz City for Science and Technology - the Kingdom
of Saudi Arabia - award number: 13-BIO2289-03. The authors also acknowledge with thanks
Science and Technology Unit, King Abdulaziz University for technical support. The
funder had no role in study design, data collection and analysis, decision to publish,
or preparation of the manuscript. The funder had no role in study design, data collection
and analysis, decision to publish, or preparation of the manuscript.
Categories
Subject:
Research Article
Subject:
Biology and Life Sciences
Subject:
Anatomy
Subject:
Endocrine System
Subject:
Thyroid
Subject:
Medicine and Health Sciences
Subject:
Anatomy
Subject:
Endocrine System
Subject:
Thyroid
Subject:
Research and Analysis Methods
Subject:
Bioassays and Physiological Analysis
Subject:
Microarrays
Subject:
Biology and Life Sciences
Subject:
Cell Biology
Subject:
Cell Processes
Subject:
Cell Cycle and Cell Division
Subject:
Biology and life sciences
Subject:
Genetics
Subject:
DNA
Subject:
DNA damage
Subject:
Biology and life sciences
Subject:
Biochemistry
Subject:
Nucleic acids
Subject:
DNA
Subject:
DNA damage
Subject:
Biology and Life Sciences
Subject:
Cell Biology
Subject:
Cell Processes
Subject:
Cell Death
Subject:
Apoptosis
Subject:
Biology and life sciences
Subject:
Genetics
Subject:
DNA
Subject:
DNA repair
Subject:
Biology and life sciences
Subject:
Biochemistry
Subject:
Nucleic acids
Subject:
DNA
Subject:
DNA repair
Subject:
Biology and Life Sciences
Subject:
Genetics
Subject:
Gene Expression
Subject:
Biology and Life Sciences
Subject:
Biochemistry
Subject:
Proteins
Subject:
Interferons
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