4
views
0
recommends
+1 Recommend
0 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: not found

      Progression, remission, regression of chronic renal diseases.

      Lancet
      Animals, Chronic Disease, Disease Progression, Drug Therapy, Combination, Female, Humans, Kidney Diseases, epidemiology, prevention & control, therapy, Kidney Failure, Chronic, Male, Primary Prevention, methods, Prognosis, Recurrence, Remission Induction, Remission, Spontaneous, Renal Dialysis, Risk Assessment, Risk Factors, Severity of Illness Index, Survival Rate

      Read this article at

      ScienceOpenPublisherPubMed
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          The prevalence of chronic renal disease is increasing worldwide. Most chronic nephropathies lack a specific treatment and progress relentlessly to end-stage renal disease. However, research in animals and people has helped our understanding of the mechanisms of this progression and has indicated possible preventive methods. The notion of renoprotection is developing into a combined approach to renal diseases, the main measures being pharmacological control of blood pressure and reduction of proteinuria. Lowering of blood lipids, smoking cessation, and tight glucose control for diabetes also form part of the multimodal protocol for management of renal patients. With available treatments, dialysis can be postponed for many patients with chronic nephropathies, but the real goal has to be less dialysis-in other words remission of disease and regression of structural damage to the kidney. Experimental and clinical data lend support to the notion that less dialysis (and maybe none for some patients) is at least possible.

          Related collections

          Author and article information

          Comments

          Comment on this article