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      Efficacy, safety and tolerability of duloxetine 60 mg once daily in major depression.

      1 , ,

      Current medical research and opinion

      Informa Healthcare

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          Abstract

          Major depressive disorders (MDD) present a significant public health problem, in terms of burden for individual sufferers, their families and society as a whole. Recently, dualacting antidepressants, which block both serotonin (5-HT) and noradrenaline (NA) reuptake, have been developed with the hope of improving depression treatment outcomes. Duloxetine is a dual reuptake inhibitor of 5-HT and NA that has recently been licensed in the USA for the treatment of MDD.

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          Author and article information

          Journal
          Curr Med Res Opin
          Current medical research and opinion
          Informa Healthcare
          0300-7995
          0300-7995
          Mar 2005
          : 21
          : 3
          Affiliations
          [1 ] Department of Psychiatry, University of Oxford, Warneford Hospital, Oxford, UK. phil.cowen@psychiatry.oxford.ac.uk
          Article
          10.1185/030079905X30680
          15811202

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