Screening of circulating microRNA biomarkers for prevalence of abdominal aortic aneurysm and aneurysm growth.

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Abstract

MicroRNA (miR) are important regulators of gene expression and biological processes and have recently been suggested as possible biomarkers for abdominal aortic aneurysm (AAA) disease. The aim of the present study was to assess the role of miR as biomarkers for initiation and progression of AAA disease, through evaluation of a wide range of miRs in a large population-based cohort, with AAA patients with linked clinical data regarding risk factors, AAA size and growth, as well as controls.

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Author and article information

Journal

Journal ID (iso-abbrev): Atherosclerosis

Title: Atherosclerosis

Publisher: Elsevier BV

ISSN (Electronic): 1879-1484

ISSN (Print): 0021-9150

Publication date (Electronic): Jan 2017

Volume: 256

Affiliations

[1 ] Department of Surgical Sciences, Section of Vascular Surgery, Uppsala University, Uppsala, Sweden.

[2 ] Division of Drug Research, Department of Medical and Health Sciences, Linköping University, Linköping, Sweden.

[3 ] Division of Medical Diagnostics, Department of Clinical Physiology, Region Jönköping County, Jönköping, Sweden; Department of Natural Science and Biomedicine, School of Health and Welfare, Jönköping University, Jönköping, Sweden.

[4 ] Division of Cardiovascular Medicine, Department of Medical and Health Sciences, Faculty of Health Sciences, Linköping University, Linköping, Sweden.

[5 ] Division of Drug Research, Department of Medical and Health Sciences, Linköping University, Linköping, Sweden. Electronic address: Dick.Wagsater@liu.se.

Article

Publisher Item ID: S0021-9150(16)31475-7

DOI: 10.1016/j.atherosclerosis.2016.11.007

PubMed ID: 27993388

SO-VID: 044b8eea-178b-479c-a083-49d61085ecca

History

Keywords: MicroRNA,Aneurysm,Biomarker,Plasma,Risk factor

Data availability:

Keywords: MicroRNA, Aneurysm, Biomarker, Plasma, Risk factor

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