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      Synergistic effects of tamoxifen and tranilast on VEGF and MMP-9 regulation in cultured human breast cancer cells.

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          Abstract

          Vascular endothelial growth factor and matrix metalloproteinases are two important factors for angiogenesis associated with breast cancer growth and progression. The present study was aimed to examine the effects of tamoxifen and tranilast drugs singly or in combination on proliferation of breast cancer cells and also to evaluate VEGF and MMP-9 expression and VEGF secretion levels.

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          Author and article information

          Journal
          Asian Pac. J. Cancer Prev.
          Asian Pacific journal of cancer prevention : APJCP
          2476-762X
          1513-7368
          2013
          : 14
          : 11
          Affiliations
          [1 ] Department of Biology, Faculty of Science, Razi University, Kermanshah, Iran E-mail : aghanbari@kums.ac.ir.
          Article
          24377619
          04576401-5ade-4709-af37-74134c750651
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