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      Nitrous oxide abuse leading to extreme homocysteine levels and thrombosis in young adults: a case series.

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          Abstract

          Neurologic complications from recreational use of nitrous oxide (N2O), which are attributed to vitamin B12 deficiency, have been well documented. With increasing dosages and frequency of N2O use, an additional association with thromboembolisms is becoming apparent.

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          Author and article information

          Journal
          J Thromb Haemost
          Journal of thrombosis and haemostasis : JTH
          Elsevier BV
          1538-7836
          1538-7836
          Feb 2023
          : 21
          : 2
          Affiliations
          [1 ] Department of Internal Medicine, OLVG, Amsterdam, the Netherlands. Electronic address: martinecaris@gmail.com.
          [2 ] Department of Cardiology, OLVG, Amsterdam, the Netherlands.
          [3 ] Department of Internal Medicine, OLVG, Amsterdam, the Netherlands.
          [4 ] Department of Neurology, OLVG, Amsterdam, the Netherlands.
          [5 ] Department of Vascular Medicine, Amsterdam University Medical Center, Location AMC, Amsterdam, the Netherlands.
          Article
          S1538-7836(22)07168-9
          10.1016/j.jtha.2022.10.002
          36700505
          048bf1c7-d7bd-45c2-adf2-856ca082d991
          History

          folic acid,hyperhomocysteinemia,nitrous oxide,thrombosis,vitamin B12

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