Journal ID (nlm-ta): PLoS One
Journal ID (iso-abbrev): PLoS ONE
Journal ID (publisher-id): plos
Journal ID (pmc): plosone
Title:
PLoS ONE
Publisher:
Public Library of Science
(San Francisco, CA USA
)
ISSN
(Electronic):
1932-6203
Publication date
(Electronic):
10
May
2017
Publication date Collection: 2017
Volume: 12
Issue: 5
Electronic Location Identifier: e0175963
Affiliations
[1
]Department of Medicine, Snyder Institute for Chronic Diseases, University of Calgary
Cumming School of Medicine, Calgary, Alberta, Canada
[2
]Department of Physiology & Pharmacology, Snyder Institute for Chronic Diseases, University
of Calgary Cumming School of Medicine, Calgary, Alberta, Canada
[3
]Department of Microbiology, Immunology and Infectious Diseases, Snyder Institute for
Chronic Diseases, University of Calgary Cumming School of Medicine, Calgary, Alberta,
Canada
University of Alabama at Birmingham, UNITED STATES
Author notes
Competing Interests: DP has received consulting fees from AstraZeneca, Janssen, Pfizer and Procter & Gamble,
and has received research grants from AstraZeneca and MedImmune. None of these applied
to the current work. RL has received consulting fees from AstraZeneca, Boehringer
Ingelheim, GlaxoSmithKline, Novartis and Janssen, and has received Research Grants
from AstraZeneca, MedImmune, GlaxoSmithKline, Novartis, Roche, Sanofi Aventis and
Amgen. None of these applied to the current work. All other authors have no competing
interests. This does not alter our adherence to PLOS ONE policies on sharing data
and materials.
-
Conceptualization: JWA CK WSL DP RL.
-
Data curation: JWA DP RL.
-
Formal analysis: JWA JCM DP RL.
-
Funding acquisition: DP RL.
-
Investigation: JWA JCM SW SLT CK CS BM CJD.
-
Methodology: JWA BM CK DP RL.
-
Project administration: DP RL.
-
Resources: CK SW SLT CJD WSL DP RL.
-
-
-
Visualization: JWA DP RL.
-
Writing – original draft: JWA DP RL.
-
Writing – review & editing: JWA JCM CK SW SLT CS BM CJD WSL DP RL.
Article
Publisher ID:
PONE-D-16-43188
DOI: 10.1371/journal.pone.0175963
PMC ID: 5425185
PubMed ID: 28489911
SO-VID: 04c72541-4b6d-4070-9c21-eeb0b19449b1
Copyright © © 2017 Arnason et al
License:
This is an open access article distributed under the terms of the
Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided
the original author and source are credited.
Funded by: funder-id http://dx.doi.org/10.13039/501100000024, Canadian Institutes of Health Research;
Award ID: 82049
Award Recipient
:
Richard Leigh
Funded by: funder-id http://dx.doi.org/10.13039/501100000024, Canadian Institutes of Health Research;
Award ID: 43923
Award Recipient
:
David Proud
Grant numbers 82049 (to RL) & 43923 (to DP) from the Canadian Institutes of Health
Research (CIHR) supported this work. Dr. Leigh holds the GlaxoSmithKline-CIHR Professorship
in Inflammatory Lung Diseases at the University of Calgary and Dr. Proud is the recipient
of a Tier 1 Canada Research Chair in Inflammatory Airway Diseases. The funders had
no role in study design, data collection and analysis, decision to publish, or preparation
of the manuscript.
Subject:
Research Article
Subject:
Medicine and Health Sciences
Subject:
Infectious Diseases
Subject:
Co-Infections
Subject:
Medicine and Health Sciences
Subject:
Pulmonology
Subject:
Chronic Obstructive Pulmonary Disease
Subject:
Biology and Life Sciences
Subject:
Immunology
Subject:
Immune System Proteins
Subject:
Immune Receptors
Subject:
Toll-like Receptors
Subject:
Medicine and Health Sciences
Subject:
Immunology
Subject:
Immune System Proteins
Subject:
Immune Receptors
Subject:
Toll-like Receptors
Subject:
Biology and Life Sciences
Subject:
Biochemistry
Subject:
Proteins
Subject:
Immune System Proteins
Subject:
Immune Receptors
Subject:
Toll-like Receptors
Subject:
Biology and Life Sciences
Subject:
Cell Biology
Subject:
Signal Transduction
Subject:
Immune Receptors
Subject:
Toll-like Receptors
Subject:
Biology and life sciences
Subject:
Genetics
Subject:
Gene expression
Subject:
Gene regulation
Subject:
Small interfering RNAs
Subject:
Biology and life sciences
Subject:
Biochemistry
Subject:
Nucleic acids
Subject:
RNA
Subject:
Non-coding RNA
Subject:
Small interfering RNAs
Subject:
Biology and Life Sciences
Subject:
Microbiology
Subject:
Bacteriology
Subject:
Bacterial Physiology
Subject:
Flagellin
Subject:
Biology and Life Sciences
Subject:
Microbiology
Subject:
Microbial Physiology
Subject:
Bacterial Physiology
Subject:
Flagellin
Subject:
Biology and Life Sciences
Subject:
Biochemistry
Subject:
Proteins
Subject:
Flagellin
Subject:
Biology and Life Sciences
Subject:
Cell Biology
Subject:
Cellular Types
Subject:
Animal Cells
Subject:
Epithelial Cells
Subject:
Biology and Life Sciences
Subject:
Anatomy
Subject:
Biological Tissue
Subject:
Epithelium
Subject:
Epithelial Cells
Subject:
Medicine and Health Sciences
Subject:
Anatomy
Subject:
Biological Tissue
Subject:
Epithelium
Subject:
Epithelial Cells
Subject:
Biology and Life Sciences
Subject:
Microbiology
Subject:
Medical Microbiology
Subject:
Microbial Pathogens
Subject:
Bacterial Pathogens
Subject:
Pseudomonas Aeruginosa
Subject:
Medicine and Health Sciences
Subject:
Pathology and Laboratory Medicine
Subject:
Pathogens
Subject:
Microbial Pathogens
Subject:
Bacterial Pathogens
Subject:
Pseudomonas Aeruginosa
Subject:
Biology and Life Sciences
Subject:
Organisms
Subject:
Bacteria
Subject:
Pseudomonas
Subject:
Pseudomonas Aeruginosa
Subject:
Medicine and Health Sciences
Subject:
Infectious Diseases
Subject:
Viral Diseases
Subject:
Rhinovirus Infection