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Functional connectivity of the anterior cingulate cortex predicts treatment outcome for rTMS in treatment-resistant depression at 3-month follow-up
October 2019
October 2019
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Abstract
<p class="first" id="d2592117e111">Repetitive transcranial magnetic stimulation (rTMS)
is a first-line treatment for
treatment-resistant depression (TRD). The mechanisms of action of rTMS are not fully
understood, and no biomarkers are available to assist in clinical practice to predict
response to rTMS. This study aimed to demonstrate that after-rTMS clinical improvement
is associated with functional connectivity (FC) changes of the subgenual cingulate
cortex (sgACC) and rostral anterior cingulate (rACC), and FC of sgACC and rACC might
serve as potential predictors for treatment response.
</p>