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      [Noncultivatable forms of Francisella tularensis].

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          Abstract

          Conditions for the appearance of F. tularensis uncultivated forms and for their reversion into the initial state have been studied. As revealed in this study, the combined influence of stress factors (starvation and low temperature) may result in the transition of F. tularensis into the uncultivated state in which it persists in the environment during the period between epidemics. The reversion of F. tularensis uncultivated forms into the initial state has been carried out with the use of sensitive animals. The uncultivated state of F. tularensis should be regarded as the actual form of the existence of the causative agent of tularemia in soil and water ecosystems.

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          Author and article information

          Journal
          Zh. Mikrobiol. Epidemiol. Immunobiol.
          Zhurnal mikrobiologii, epidemiologii, i immunobiologii
          0372-9311
          0372-9311
          May 16 2000
          : 2
          Affiliations
          [1 ] Research Institute for Plague Control, Rostov-on-Don, Russia.
          Article
          10808564
          04e8708e-c0f2-43cb-b6d9-174fdf034c63
          History

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