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      Topical tacrolimus in dermatology.

      1
      Clinical and experimental dermatology
      Wiley

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          Abstract

          Tacrolimus and cyclosporin A are potent immunosuppressants that are used systemically to treat several inflammatory skin conditions successfully. They differ in their structure and tacrolimus is 10-100 times more potent than cyclosporin A. They have similar side-effects. They have been used topically in various clinical studies. Topical cyclosporin A is largely ineffective whereas topical tacrolimus is effective in treating atopic dermatitis. Topical tacrolimus has not been studied sufficiently in treating psoriasis although it has been used successfully in allergic contact dermatitis, erosive mucosal lichen planus and pyoderma gangrenosum.

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          Author and article information

          Journal
          Clin Exp Dermatol
          Clinical and experimental dermatology
          Wiley
          0307-6938
          0307-6938
          May 2000
          : 25
          : 3
          Affiliations
          [1 ] Consultant Dermatologist, Scunthorpe General Hospital, Scunthorpe, North Lincolnshire, UK. isinasr@quista.nct
          Article
          ced628
          10.1046/j.1365-2230.2000.00628.x
          10844509
          0507aa94-2b28-4bf6-9e4e-e9b8fa2a05f8
          History

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