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      Valuation of EQ-5D-5L Health States in Poland: the First EQ-VT-Based Study in Central and Eastern Europe

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          Abstract

          Objective

          Cost-utility analyses are becoming increasingly important in Central and Eastern Europe. We aimed to develop a Polish utility tariff for EQ-5D-5L health states.

          Methods

          Face-to-face, computer-assisted interviews were collected in a representative sample. Each respondent followed a standardised protocol to collect ten composite time trade-off and seven discrete choice experiment observations. In the Bayesian approach, several model specifications were compared based on model fit, the usability of the final value set and how they reflect the elicitation procedure (e.g. censoring). A hybrid approach (using composite time trade-off and discrete choice experiment data) was employed in the final set, which was compared with the existing ones: EQ-5D-3L and EQ-5D-5L cross-walk.

          Results

          Data from 1252 respondents (11,480 composite time trade-off valuations and 8764 discrete choice experiment pairs) were collected over the period June to October 2016. The final model accounted for random parameters, error scaling with fat tails, censoring at − 1, unwillingness to trade in time trade-off by the religious people and Cauchy distribution in discrete choice experiments. Pain/discomfort impacts the utility most: the disutility equals 0.575 when at level 5. In the value set, 4.4% of EQ-5D-5L states are worse than dead. The new value set has a comparable range (minimum of − 0.590 compared to − 0.523) and the same ordering of the first three dimensions (pain/discomfort, mobility, self-care) as the EQ-5D-3L value set and the EQ-5D-5L cross-walk value set. Moreover, it is more sensitive to a moderate decline in health.

          Conclusions

          The new value set supports consistency with past decisions in cost-utility studies, while offering a better assessment of even moderate improvements in health. It could represent an option for Central and Eastern Europe countries lacking their own value sets.

          Electronic supplementary material

          The online version of this article (10.1007/s40273-019-00811-7) contains supplementary material, which is available to authorized users.

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          Most cited references 37

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          A program of methodological research to arrive at the new international EQ-5D-5L valuation protocol.

          To describe the research that has been undertaken by the EuroQol Group to improve current methods for health state valuation, to summarize the results of an extensive international pilot program, and to outline the key elements of the five-level EuroQol five-dimensional (EQ-5D-5L) questionnaire valuation protocol, which is the culmination of that work.
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            Estimating an EQ-5D-5L Value Set for China.

            To estimate a five-level EuroQol five-dimensional questionnaire (EQ-5D-5L) value set for China using the health preferences of residents living in the urban areas of the country.
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              The EQ-5D-5L valuation study in Korea.

              This study aimed to estimate Korean preference weights for EQ-5D-5L based on values elicited from Korean population by applying the EuroQol Valuation Technology (EQ-VT) program and the standard protocol by the EuroQol Group.
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                Author and article information

                Contributors
                +48 501 078 203 , dominik.golicki@wum.edu.pl
                michal.jakubczyk@sgh.waw.pl
                katarzyna.graczyk88@gmail.com
                maciej.niewada@wum.edu.pl
                Journal
                Pharmacoeconomics
                Pharmacoeconomics
                Pharmacoeconomics
                Springer International Publishing (Cham )
                1170-7690
                1179-2027
                3 June 2019
                3 June 2019
                2019
                : 37
                : 9
                : 1165-1176
                Affiliations
                [1 ]ISNI 0000000113287408, GRID grid.13339.3b, Department of Experimental and Clinical Pharmacology, , Medical University of Warsaw, ; Banacha 1b St., 02-097 Warsaw, Poland
                [2 ]ISNI 0000 0001 2097 5735, GRID grid.426142.7, Decision Analysis and Support Unit, , SGH Warsaw School of Economics, ; Al. Niepodległości 162, 02-554 Warsaw, Poland
                [3 ]HealthQuest Spółka z ograniczoną odpowiedzialnością Sp. k., 63 Mickiewicza Street, Megadex A Building, 01-625 Warsaw, Poland
                Article
                811
                10.1007/s40273-019-00811-7
                6830402
                31161586
                © The Author(s) 2019

                Open AccessThis article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License ( http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

                Funding
                Funded by: FundRef http://dx.doi.org/10.13039/501100006419, EuroQol Research Foundation;
                Award ID: EQ Project 2015240
                Award Recipient :
                Funded by: HealthQuest, Warsaw (PL)
                Award ID: 1/2016
                Award Recipient :
                Categories
                Original Research Article
                Custom metadata
                © Springer Nature Switzerland AG 2019

                Economics of health & social care

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