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      Reperfusion therapies and in-hospital outcomes for ST-elevation myocardial infarction in Europe: the ACVC-EAPCI EORP STEMI Registry of the European Society of Cardiology

      1 , 2 , 3 , 4 , 5 , 6 , 7 , 8 , 9 , 10 , 11 , 12 , 13 , 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 ,   5 , 33 , 34 , on behalf of the ACVC EAPCI EORP ACS STEMI investigators group of the ESC
      European Heart Journal
      Oxford University Press (OUP)

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          Abstract

          Aims

          The aim of this study was to determine the contemporary use of reperfusion therapy in the European Society of Cardiology (ESC) member and affiliated countries and adherence to ESC clinical practice guidelines in patients with ST-elevation myocardial infarction (STEMI).

          Methods and results

          Prospective cohort (EURObservational Research Programme STEMI Registry) of hospitalized STEMI patients with symptom onset <24 h in 196 centres across 29 countries. A total of 11 462 patients were enrolled, for whom primary percutaneous coronary intervention (PCI) (total cohort frequency: 72.2%, country frequency range 0–100%), fibrinolysis (18.8%; 0–100%), and no reperfusion therapy (9.0%; 0–75%) were performed. Corresponding in-hospital mortality rates from any cause were 3.1%, 4.4%, and 14.1% and overall mortality was 4.4% (country range 2.5–5.9%). Achievement of quality indicators for reperfusion was reported for 92.7% (region range 84.8–97.5%) for the performance of reperfusion therapy of all patients with STEMI <12 h and 54.4% (region range 37.1–70.1%) for timely reperfusion.

          Conclusions

          The use of reperfusion therapy for STEMI in the ESC member and affiliated countries was high. Primary PCI was the most frequently used treatment and associated total in-hospital mortality was below 5%. However, there was geographic variation in the use of primary PCI, which was associated with differences in in-hospital mortality.

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          Most cited references19

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          2017 ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation

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            2015 ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation: Task Force for the Management of Acute Coronary Syndromes in Patients Presenting without Persistent ST-Segment Elevation of the European Society of Cardiology (ESC).

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              Standardized bleeding definitions for cardiovascular clinical trials: a consensus report from the Bleeding Academic Research Consortium.

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                Author and article information

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                Journal
                European Heart Journal
                Oxford University Press (OUP)
                0195-668X
                1522-9645
                August 14 2021
                August 14 2021
                Affiliations
                [1 ]Klinikum der Stadt Ludwigshafen and Institut für Herzinfarktforschung, Bremserstraße 79, 67063 Ludwigshafen am Rhein, Germany
                [2 ]Institute of Cardiovascular Sciences, University of Birmingham, Edgbaston 1, Birmingham, B15 2TT, United Kingdom
                [3 ]Hôpital Européen Georges Pompidou, Service de Cardiologie, 20 Rue Leblanc, 75015 Paris, France
                [4 ]University Hospital Brno, Medical Faculty of Masaryk University, Dept of Internal Medicine and Cardiology, Kamenice 5, 625 00 Bohunice, Brno, Czech Republic
                [5 ]EURObservational Research Programme, European Society of Cardiology, European Heart House, 2035 Route des Colles, Sophia Antipolis, France
                [6 ]Cardiac Rehabilitation Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Shahid Rahmani Alley, Moshtagh Sevom Street, Isfahan, Iran
                [7 ]Interventional Cardiology Unit, Annunziata Civil Hospital, Via Migliori 1, 87100 Cosenza, Italy
                [8 ]Ain shams University, Ramsis Street, Abbassia Square, Cairo, Egypt
                [9 ]Jagiellonian University Medical College; Institute of Cardiology, Department of Interventional Cardiology, John Paul II Hospital, Prądnicka 80, 31-202 Kraków, Poland
                [10 ]Rabin Medical Center, Zeev Jabotinsky St 39, Petah Tikva, 49100 Israel
                [11 ]Department of Cardiac Sciences, King Fahad Cardiac Center, College of Medicine, King Saud University, Riyadh, Saudi Arabia
                [12 ]Cardiocenter, Third Faculty of Medicine Charles Univ. and Univ. Hospital Kralovske Ruská 2411, 100 00 Praha 10-Vinohrady, Czech Republic
                [13 ]Teaching Hospital of J.A. Reiman, Cardiocentre Prešov, Jána Hollého 5898/14, 081 81 Prešov, Slovakia
                [14 ]Centro Hospitalar e Universitário do Algarve, R. Leao Penedo, 8000-386 Faro, Portugal
                [15 ]Deputy-Director of the Heart and Vascular Center of Semmelweis University, Gaál József út 9, 1122 Budapest, Hungary
                [16 ]National and Kapodistrian University of Athens, Attikon University Hospital, Rimini 1, Chaidari 124 62, Greece
                [17 ]Chapidze Emergency Cardiology Center, 0159, Didube-Chugureti District, Nino Javakhishvili str., Tbilisi, Georgia
                [18 ]Faculty of Medicine, University of Belgrade, Belgrade, Serbia. Department of Cardiology, Clinical Center of Serbia, Pasterova 2, Beograd 11000 Belgrade, Serbia
                [19 ]Scientific Research Institute of Cardiology named after Levon Hovhannisyan, 0014, Yerevan, Paruyr Sevaki St., 5 Building (Kanaker-Zeytun adm. district), Yerevan, Armenia
                [20 ]Cardiology I & Cardiology II, University Hospital Center Mother Theresa, Rruga e Dibrës 372 Tirana AL, 1000, Albania
                [21 ]Kyrgyz State Medical Academy, 92 Akhunbayev St, Bishkek, Kyrgyzstan
                [22 ]National Center of Cardiology and Internal Medicine, Togolok Moldo Str., 720040, Bishkek, Kyrgyzstan
                [23 ]Medical Faculty, University of Prishtina "Hasan Prishtina", University Clinical Centre of Kosova, Pristina 10000, Kosovo
                [24 ]Iraqi Scientific Council of Cardiology, Baghdad Heart Center, Medical City, Baghdad, Iraq
                [25 ]Vilnius University Faculty of Medicine Hospital Santaros Klinikos, 08406, Santariškių g. 2, Vilnius 08410, Lithuania
                [26 ]Aalborg University Hospital, Department of Cardiology, Hobrovej 18-22, 9100 Aalborg, Denmark
                [27 ]North Estonia Medical Centre, J. Sütiste tee 19, 13419 Tallinn, Estonia
                [28 ]Mater Dei Hospital, Triq Dun Karm, L-Imsida, MSD2090 Msida, Malta
                [29 ]St Vincent’s University Hospital, Merrion Rd, Dublin 4, D04 N2E0, Ireland
                [30 ]Satakunta Cental Hospital, Sairaalantie 3, 28500 Pori, Finland
                [31 ]Spitalul Clinic de Urgenta "Floreasca", Calea Floreasca 8, București 014461, Romania
                [32 ]Leeds Institute for Cardiovascular and Metabolic Medicine, University of Leeds School of Medicine, Worsley Building, University of Leeds, LS2 9JT Leeds, UK
                [33 ]Maria Cecilia Hospital, GVM Care & Research, Via Corriera, 1, 48033 Cotignola RA, Italy
                [34 ]Hospital Rudolfstiftung, Juchgasse 25, 1030 Wien, Austria
                Article
                10.1093/eurheartj/ehab342
                34389857
                0589599a-2faa-4a99-b38f-5d23ca540a1e
                © 2021

                https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model

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