Serumspiegel des Tumormarkers CA 125 vor der Second-look-Laparotomie beim primären epithelialen Ovarialkarzinom in Relation zu intraoperativen Befunden

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Abstract

Bei 76 Patientinnen erfolgte die serologische Bestimmung des Tumormarkers CA 125 vor der Second-look-Operation beim primären epithelialen Ovarialkarzinom. Diese Befunde wurden mit dem operativ erhobenen intraabdominalen Tumorstatus verglichen. Die Serumspiegel des Tumormarkers CA 125 waren bei 26 Frauen in Übereinstimmung mit dem operativen Tumornachweis über 35 U/ml erhöht. Während sich bei 29 Patientinnen mit normalen CA-125-Spiegeln makroskopisch und mikroskopisch keine Tumormanifestation ergab, fand sich in 21 Fallen mit normalen CA-125-Befunden Karzinomgewebe. Erhöhte CA-125-Spiegel hatten einen hohen prädiktiven Wert hinsichtlich des intraabdominalen Tumornachweises. Wegen der geringen Sensitivität können serologische Kontrollen des Tumormarkers CA 125 die Second-look-Laparotomie nicht ersetzen.

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Journal ID (publisher-id): ONK

Journal ID (nlm-ta): Oncol Res Treat

Journal ID (doi): 10.1159/issn.2296-5270

Title: Oncology Research and Treatment

Publisher: S. Karger AG

ISSN (Print): 2296-5270

ISSN (Electronic): 2296-5262

Publication date Subscription-year: 1989

Publication date (Print): 1989

Publication date (Electronic): 27 April 2009

Volume: 12

Issue: 5

Pages: 217-220

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Universitäts-Frauenklinik Göttingen (Leiter: Prof. Dr. med. W. Kuhn)

Article

Publisher ID: 216648 Other ID: Onkologie 1989;12:217–220

DOI: 10.1159/000216648

PubMed ID: 2685687

SO-VID: 066b7bd9-b8b2-4b59-8608-e8535b41e4ca

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Serumspiegel des Tumormarkers CA 125 vor der Second-look-Laparotomie beim primären epithelialen Ovarialkarzinom in Relation zu intraoperativen Befunden

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Karger: Oncology

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