Risk of Heroin Dependence in Newly Incident Heroin Users

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Abstract

<p class="first" id="d9663687e279">This study assesses data from the 2002 to 2016 US National Survey on Drug Use and Health data sets to determine the percentage of newly incident heroin users who became heroin dependent. </p>

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Most cited references 3

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Comparative epidemiology of dependence on tobacco, alcohol, controlled substances, and inhalants: Basic findings from the National Comorbidity Survey.

James Anthony, Lynn A. Warner, Ronald C Kessler (1994)

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Changes in US Lifetime Heroin Use and Heroin Use Disorder: Prevalence From the 2001-2002 to 2012-2013 National Epidemiologic Survey on Alcohol and Related Conditions.

Silvia S. Martins, Aaron L Sarvet, Julian Santaella-Tenorio … (2017)

Heroin use is an urgent concern in the United States. Little is know about the course of heroin use, heroin use disorder, and associated factors.

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Epidemiological evidence on extra-medical use of prescription pain relievers: transitions from newly incident use to dependence among 12–21 year olds in the United States using meta-analysis, 2002–13

Maria Parker, James Anthony (2015)

Background. When 12-to-21-year-olds start using prescription pain relievers extra-medically, some of them transition into opioid dependence within 12 months after such use. Our main aim for this epidemiological research on 12-to-21-year-olds in the United States (US) is to estimate the risk of becoming a newly incident case of opioid dependence within 12 months after onset of using prescription pain relievers extra-medically (EMPPR). Methods. Meta-analyses from multiple independent replication samples now are possible, based upon nationally representative survey samples of US adolescents age 12–21 years. All 12-to-21-year-olds were sampled and recruited for the US National Surveys on Drug Use and Health, with standardized assessments of EMPPR use and opioid dependence (NSDUH, 2002–2013). Results. Peak risk for a transition from start of EMPPR use to opioid dependence within 12 months is seen at mid-adolescence among 14-to-15-year-olds (6.3%, 8.7% per year), somewhat earlier than peak risk for starting EMPPR use (seen for 16-to-19-year-olds at 4.1%, 5.9% per year). Applied to 12-to-21-year-olds in the US between 2002–2013, an estimated 8 million started using PPR extra-medically. Each year, roughly 42,000 to 58,000 transitioned into opioid dependence within 12 months after onset of such use. Discussion. These epidemiological estimates for the US in recent years teach us to expect one transition into adolescent-onset opioid dependence within 12 months for every 11–16 newly incident EMPPR users, yielding perhaps 120 newly incident opioid dependent cases in need of practitioner attention or treatment services, each day of each year. This evidence can be used to motivate more effective public health prevention, outreach, and early intervention programs as might prevent or delay occurrence of EMPPR use and opioid dependence.

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Journal

Title: JAMA Psychiatry

Abbreviated Title: JAMA Psychiatry

Publisher: American Medical Association (AMA)

ISSN (Print): 2168-622X

Publication date Created: August 01 2018

Publication date (Print): August 01 2018

Volume: 75

Issue: 8

Page: 863

Affiliations

[1 ]Department of Epidemiology and Biostatistics, Michigan State University, East Lansing

[2 ]Center on Drug and Alcohol Research, Department of Behavioral Science, University of Kentucky College of Medicine, Lexington

[3 ]Vermont Center on Behavior and Health, University of Vermont, Burlington

Article

DOI: 10.1001/jamapsychiatry.2018.1214

PMC ID: 6584277

PubMed ID: 29847618

SO-VID: 069ea8f5-9afd-4047-8c25-73da82487d8b

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Risk of Heroin Dependence in Newly Incident Heroin Users

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Most cited references 3

Comparative epidemiology of dependence on tobacco, alcohol, controlled substances, and inhalants: Basic findings from the National Comorbidity Survey.

Changes in US Lifetime Heroin Use and Heroin Use Disorder: Prevalence From the 2001-2002 to 2012-2013 National Epidemiologic Survey on Alcohol and Related Conditions.

Epidemiological evidence on extra-medical use of prescription pain relievers: transitions from newly incident use to dependence among 12–21 year olds in the United States using meta-analysis, 2002–13

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