Objective To explore the relationship between distortion product otoacoustic emission (DPOAE) test and pure tone audiometry (PTA), and the application of DPOAE test in occupational health inspection of noise-exposed work.
Methods Using the judgment sampling method, 510 noise-exposed workers in an automobile engine factory were selected as the observation group. The observation group was divided into 5 subgroups according to the characteristics of PTA threshold and frequency of hearing loss. Another 50 non-noise-exposed workers in the factory were selected as the control group. DPOAE and PTA were used to detect the pure tone hearing threshold and DPOAE amplitude, signal-to-noise ratio and pass rate of each frequency in the two groups of workers.
Results At 0.5-6.0 kHz, the pure tone hearing threshold value of each subgroup was higher than the control group (all P<0.05). At 3.0-6.0 kHz, the DPOAE amplitude and signal-to noise ratio of each subgroup were lower than that of the control group (all P<0.05). At 1.5 kHz, the pass rate of DPOAE in subgroup 1, subgroup 2 and subgroup 3 were higher than the control group (all P<0.05). At 2.0-6.0 kHz, the pass rate of DPOAE in subgroup 4 and subgroup 5 were lower than the control group (all P<0.05). The area receiver operating characteristic curve (AUC) of the observation subgroups and control group were 0.71-1.00 by the PTA. The AUC values of the observation subgroups and control group were 0.57-0.97 by DPOAE. The AUC value in subgroup 5 and control group had a significant difference between the two examination methods ( P< 0.01); while the subgroup 1, subgroup 2, subgroup 3, subgroup 4 and control group were no significant differences respectively (all P>0.05).
Conclusion DPOAE is easy to operate and can objectively reflect the hearing level of workers exposed to noise. It can be used as a supplementary means of PTA and applied to occupational health examination and hearing monitoring screening.
摘要: 目的 探讨畸变产物耳声发射(DPOAE)测试与纯音测听的关系, 以及DPOAE测试在噪声作业职业健康检査中的 应用。 方法 采用判断抽样方法, 选择某汽车发动机厂 510 名噪声作业工人为观察组, 观察组人群根据纯音测听单耳听 阈值以及听力损失频率的特点分为 5 个观察亚组;另选择该厂 50 名非噪声作业工人为对照组。采用DPOAE和纯音测听 检査检测 2 组人群各频率的纯音听阈及DPOAE的幅值、信噪比、通过率。 结果 在 0.5 ~ 6.0 kHz, 5 个观察亚组人群的纯 音听阈值均髙于对照组 ( P 值均<0.05) 在 3.0 ~ 6.0 kHz, 5 个观察亚组人群的DPOAE信号幅值和信噪比分别低于对照组 ( P 值均<0.05)。在 1.5 kHz, 观察亚组 1、观察亚组 2 和观察亚组 3 人群的 DPOAE 检査通过率均髙于对照组 ( P 值均<0.05); 在2.0 ~ 6.0 kHz, 观察亚组 4 和观察亚组 5 人群的DPOAE检査通过率均低于对照组 ( P 值均<0.05)。采用纯音测听 检査方法, 各观察亚组与对照组人群的工作特征曲线下的面积 (AUC) 值为 0.71 ~ 1.00; 采用DPOAE检査方法, 各观察亚 组与对照组人群的AUC值为 0.57 ~ 0.97; 2 种检査方法的 AUC 值比较, 观察亚组 1、观察亚组 2、观察亚组 3、观察亚组 4 分 别与对照组比较, 差异均无统计学意义 ( P 值均>0.05); 仅观察亚组 5 与对照组比较, 差异有统计学意义 ( P<0.01)。 结论 DPOAE 检査操作便捷, 可客观反映噪声作业工人的听力水平, 可作为纯音测听检査的补充检査手段, 应用于职业健康检 査与听力监测筛査。