Aqueous extract obtained from deoiled neem and karanja seed kernels (ADNSD and ADKSK) were assessed for their toxic and growth regulating activities against Cx quinquefaciatus treated as first instar larvae. ADNSK at various concentrations was effective on the growth regulating mechanism, inducing prolonged larval stages. However, 100% larval mortality was observed, especially during the first and the second instars at all the tested concentrations. ADKSK caused 100% mortality in the fourth instar larvae and prepupae at the concentration of 100 ppm with no significant effect on the developmental period. The adults emerging from treated (50 ppm) larvae were smaller in size and malformed. We found ADNSK to be more effective than ADKSK.