+1 Recommend
1 collections
      Are you tired of sifting through news that doesn't interest you?
      Personalize your Karger newsletter today and get only the news that matters to you!

      Sign up

      • Record: found
      • Abstract: found
      • Article: found

      Trabeculectomy with Long-Term-Stored Mitomycin C in a West Indian Population

      a , b , b
      S. Karger AG
      Caribbean, Glaucoma, Trabeculectomy, Mitomycin C

      Read this article at

          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.


          We investigated the outcome of trabeculectomy with stored mitomycin C (MMC) in a black Caribbean population on the island of Dominica. Ten eyes (9 patients) underwent trabeculectomy with MMC (0.5 mg/ml for 3–6 min) that had been stored for up to 17 months at 4 °C. The preoperative intraocular pressure of (mean ± SD) 32.8±7.5 mm Hg on 2.6 medications decreased to 9.5±3.2 mm Hg on 0.2 medications after a mean follow-up time of 14.2 months (range 7–25). Nine eyes did not receive medications postoperatively. Complications observed included bleb infection (1 eye) and late bleb leak (1 eye); 2 eyes developed cataract. Nine blebs had typical clinical features of blebs after trabeculectomy with adjunctive MMC. We conclude that long-term-stored MMC may be beneficial as adjunctive treatment in initial trabeculectomy in this population.

          Related collections

          Author and article information

          S. Karger AG
          December 1998
          23 September 1998
          : 212
          : 6
          : 404-406
          aDepartment of Ophthalmology, University of Washington, Seattle, Wash., USA; bPrincess Margaret Hospital and Clinics,& ;Roseau, Dominica
          27376 Ophthalmologica 1998;212:404–406
          © 1998 S. Karger AG, Basel

          Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

          Page count
          Tables: 1, References: 14, Pages: 3
          Original Paper · Travail original · Originalarbeit

          Vision sciences,Ophthalmology & Optometry,Pathology
          Glaucoma,Trabeculectomy,Mitomycin C,Caribbean
          Vision sciences, Ophthalmology & Optometry, Pathology
          Glaucoma, Trabeculectomy, Mitomycin C, Caribbean


          Comment on this article