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      Association between traffic-related air pollution and development of asthma in school children: cohort study in Japan.

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          Abstract

          Air pollution is widely understood to be capable of exacerbating asthma symptoms. Here we examined the association between traffic-related air pollution and development of asthma in school children. Subjects were 10,069 school children in their first through third years of compulsory education (6-9-year old). The main outcome was incidence of asthma as determined from the questionnaire. Follow-up surveys were conducted every year up to 4 years after the end of the study. To evaluate individual level of exposure to traffic-related air pollution, we used a simulation model that accounted for exposure level both at home and at school. As surrogates of traffic-related air pollution, the estimation target was the annual average individual exposure of automobile exhaust-originating nitrogen oxides (NOx) and elemental carbon (EC). Confounding factors were adjusted using a discrete-time logistic regression model. We found a positive association between exposure to EC and incidence of asthma. The odds ratio (OR) (95% confidence interval) for asthma incidence was 1.07 (1.01-1.14) for each 0.1 μg/m(3) EC and 1.01 (0.99-1.03) for each 1 p.p.b. NOx. Traffic-related air pollution is associated with development of asthma in school children.

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          Author and article information

          Journal
          J Expo Sci Environ Epidemiol
          Journal of exposure science & environmental epidemiology
          Springer Nature
          1559-064X
          1559-0631
          Jul 2014
          : 24
          : 4
          Affiliations
          [1 ] Department of Healthcare Epidemiology, Kyoto University School of Public Health, Kyoto, Japan.
          [2 ] Department of Public Health, Hyogo College of Medicine, Nishinomiya, Japan.
          [3 ] Department of Hygiene, Showa University, Tokyo, Japan.
          [4 ] Center for Regional Environmental Research, National Institute for Environmental Studies, Tsukuba, Japan.
          [5 ] Faculty of Culture and Information Science, Doshisha University, Kyoto, Japan.
          [6 ] Center for Environmental Health Sciences, National Institute for Environmental Studies, Tsukuba, Japan.
          [7 ] Department of Biostatistics, Kyoto University School of Public Health, Kyoto, Japan.
          Article
          jes201415
          10.1038/jes.2014.15
          24619296
          070b3040-dd12-48a2-946d-97c1e0bd9a51
          History

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