Gastrectomy plus chemotherapy versus chemotherapy alone for advanced gastric cancer with a single non-curable factor (REGATTA): a phase 3, randomised controlled trial.

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Abstract

Chemotherapy is the standard of care for incurable advanced gastric cancer. Whether the addition of gastrectomy to chemotherapy improves survival for patients with advanced gastric cancer with a single non-curable factor remains controversial. We aimed to investigate the superiority of gastrectomy followed by chemotherapy versus chemotherapy alone with respect to overall survival in these patients.

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Journal

Journal ID (iso-abbrev): Lancet Oncol.

Title: The Lancet. Oncology

Publisher: Elsevier BV

ISSN (Electronic): 1474-5488

ISSN (Print): 1470-2045

Publication date (Electronic): Mar 2016

Volume: 17

Issue: 3

Affiliations

[1 ] Department of Surgery, Osaka Prefectural General Medical Centre, Osaka, Japan.

[2 ] Department of Surgery, Seoul National University College of Medicine, Seoul, South Korea.

[3 ] Japan Clinical Oncology Group Data Centre/Operations Office, National Cancer Centre, Tokyo, Japan.

[4 ] Department of Surgery, National Cancer Centre, Seoul, South Korea.

[5 ] Department of Gastric Surgery, Shizuoka Cancer Centre, Shizuoka, Japan.

[6 ] Department of Surgery, Ajou University School of Medicine, Suwon, South Korea.

[7 ] Department of Surgery, Tokyo Metropolitan Komagome Hospital, Tokyo, Japan.

[8 ] Department of Surgery, Yonsei University College of Medicine, Seoul, South Korea.

[9 ] Department of Surgery, Hakodate Goryokaku Hospital, Hakodate, Japan.

[10 ] Department of Surgery, Kanagawa Cancer Centre, Yokohama, Japan.

[11 ] Medical Research Collaborating Centre, Seoul National University College of Medicine, Seoul, South Korea.

[12 ] Department of Surgery, The Catholic University of Korea, Seoul St Mary's Hospital, Seoul, South Korea.

[13 ] Department of Gastrointestinal Surgery, Osaka University Graduate School of Medicine, Osaka, Japan.

[14 ] Department of Internal Medicine, Seoul National University College of Medicine, Seoul, South Korea.

[15 ] Department of Surgery, Hyogo College of Medicine, Nishinomiya, Japan.

[16 ] Department of Surgery, Kaizuka City Hospital, Osaka, Japan. Electronic address: tsujinaka@hosp.kaizuka.osaka.jp.

Article

Publisher Item ID: S1470-2045(15)00553-7

DOI: 10.1016/S1470-2045(15)00553-7

PubMed ID: 26822397

SO-VID: 070bbd92-446f-4b08-95cc-88a0197f31f2

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