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      To wear or not to wear a mask in the COVID-19 era? The broken bridge between recommendations and implementation in Lebanon

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      Journal of Global Health
      International Society of Global Health

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          Abstract

          At the beginning of the COVID-19 pandemic, the scientific community has been debating the use of face masks amongst the general public, sending conflicting recommendations. On one side, the World Health Organization (WHO) did not recommend using face masks as a preventive measure [1], in the absence of extensive scientific evidence on the matter. Till May 2020, there were no high quality controlled trials addressing the question of wearing masks by the general population as a protective measure to contain COVID-19. In the absence of evidence related explicitly to COVID-19, analogies were be made with similar types of viruses with high transmission rates, such as influenza or SARS. A recent meta-analysis looking into the effectiveness of the public’s use of non-pharmaceutical interventions in the transmission of influenza did not report supporting evidence for the use of face masks [2]. With the lack of strong evidence, the absence of supportive recommendations became more meaningful when considering the shortages of personal protective equipment, including face masks needed for health care workers worldwide. Meanwhile, some public health agencies, such as the US Centers for Disease Control and Prevention (CDC), initially aligned with WHO’s recommendations, has later shifted to recommend the use of “cloth face coverings” [3] as a way to reduce the spreading of the virus. The European Centers for Disease Control and Prevention (ECDC) adopted a more cautious approach while highlighting the caveats of improper use and stating that wearing non-medical masks may be considered in situations where proper physical distancing cannot be maintained [4]. The rationale for this approach may be based on various assumptions: some recent evidence showed that COVID-19 is transmitted by asymptomatic people [5]; there was some evidence suggesting that people wearing face masks were less likely to transmit influenza compared to people not wearing face masks [6]; and mathematical modeling that pointed to around 20% decrease in transmission of influenza with the use of face masks by the public [7]. Another argument in support of the use of masks is the “precautionary principle” suggested in a recent systematic review [8], where Greenhalgh and colleagues argued that the benefits of using masks outweigh the risks of creating potential harm. Amidst these opposing views and despite the lack of clear guidance and for rational use of face masks [9], countries have adopted a variety of recommendations, some following the mandatory face masks policies adopted in Asian countries [9]. However, little is known about how state decisions are made and followed in settings with weak health and public policy systems, such as Lebanon or similar countries in the Middle East and North Africa region. In fact, the notion and type of benefits o harm from mass use of face masks vary in each context and warrants assessment based on the prevailing conditions and social norms in a given population. Lebanon still follows many laws inherited from the Ottoman Empire and the French mandate, and current policies are based on common law, instead of evidence. In the absence of clear national social and health policies and unified health promotion strategies, the private sector provides out of pocket curative care. The state constitution has allowed the personal status codes to be ruled by sectarian courts, while prominent state positions continue to be allocated to persons affiliated to sects instead of being appointed by merit or competence. Inherent economic post-civil war decline, social inequalities, mismanagement of national resources, and environmental degradation plague the country. These factors have created a chronic mistrust in the state and its ruling elite. In response to these dire conditions, a national revolution started in October 2019. The COVID-19 pandemic hit the country on February 21, 2020, and the newly formed government scrambled to put together an action plan in response, succeeding in flattening the curve but with huge economic costs borne by the population. The use of face masks has been extensively enforced throughout this outbreak. Despite the imposed public health measures of physical distancing, quarantine, and lockdown, the state health authority seems to have adopted a biomedical approach in this matter, rather than a systemic, holistic public health perspective. In this highly medicalized society, the mandatory use of face masks is another example of how clinical settings are extrapolated to the community and how global trends are adopted without critically considering the local context, implementation challenges, and long-term consequences. The enforcement of such regulation has resulted in reality with potentially adverse impacts on the course of the outbreak. Using masks without proper instructions has given people a false sense of security, leading them to disregard physical distancing. According to the WHO’s guidance, this is one of the major factors that policymakers should consider before recommending the use of face masks [1]. Self-contamination is highly probable, as people are seen repeatedly touching their faces while wearing masks, positioning them below their mouths when speaking and removing them often and improperly. Improper use of face masks is also seen among government officials when appearing on the local media and reporting about the outbreak. Disposable masks are also littering streets, exacerbating the environmental health problems amidst the lack of a waste management strategy. In a country lagging in evidence-based health policies, the risks and benefits of wearing masks are not weighed when making such recommendations. Yet, face masks are implicitly enforced in some public spaces. It was ironic to witness security forces mandating the use of face masks for people driving alone in a car, knowing well that seatbelt use is not enforced, despite a long-standing road safety law, which includes seat belt use. In a collectivist culture such as Lebanon, there is a need for contextualized, tailored communication on the notion of physical distancing in order to minimize the implementation challenges of the use of face masks by the public and the false sense of security they foster. Considering the impact of this pandemic, assumptions of a low level of harm [9] cannot apply universally, and there is a need to evaluate the impact of mass use of face masks in the Lebanese context. Photo: From https://www.barfuss.it/file/claudio-schwarz-purzlbaum-zh-btvpbcdw-unsplashjpg. Currently, governments embarking in easing the restrictive measures of the lockdown are considering recommendations about the use of face masks by the general public. There is an urgent need for health authorities to follow effective risk communication guidelines [10] and provide the rationale and clear instructions for using face masks, while reinforcing the primary messages of physical distancing and hand hygiene [1]. In the absence of such efforts, we might witness a situation where face masks will result in more harm than good for the general public.

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          SARS-CoV-2 Viral Load in Upper Respiratory Specimens of Infected Patients

          To the Editor: The 2019 novel coronavirus (SARS-CoV-2) epidemic, which was first reported in December 2019 in Wuhan, China, and has been declared a public health emergency of international concern by the World Health Organization, may progress to a pandemic associated with substantial morbidity and mortality. SARS-CoV-2 is genetically related to SARS-CoV, which caused a global epidemic with 8096 confirmed cases in more than 25 countries in 2002–2003. 1 The epidemic of SARS-CoV was successfully contained through public health interventions, including case detection and isolation. Transmission of SARS-CoV occurred mainly after days of illness 2 and was associated with modest viral loads in the respiratory tract early in the illness, with viral loads peaking approximately 10 days after symptom onset. 3 We monitored SARS-CoV-2 viral loads in upper respiratory specimens obtained from 18 patients (9 men and 9 women; median age, 59 years; range, 26 to 76) in Zhuhai, Guangdong, China, including 4 patients with secondary infections (1 of whom never had symptoms) within two family clusters (Table S1 in the Supplementary Appendix, available with the full text of this letter at NEJM.org). The patient who never had symptoms was a close contact of a patient with a known case and was therefore monitored. A total of 72 nasal swabs (sampled from the mid-turbinate and nasopharynx) (Figure 1A) and 72 throat swabs (Figure 1B) were analyzed, with 1 to 9 sequential samples obtained from each patient. Polyester flock swabs were used for all the patients. From January 7 through January 26, 2020, a total of 14 patients who had recently returned from Wuhan and had fever (≥37.3°C) received a diagnosis of Covid-19 (the illness caused by SARS-CoV-2) by means of reverse-transcriptase–polymerase-chain-reaction assay with primers and probes targeting the N and Orf1b genes of SARS-CoV-2; the assay was developed by the Chinese Center for Disease Control and Prevention. Samples were tested at the Guangdong Provincial Center for Disease Control and Prevention. Thirteen of 14 patients with imported cases had evidence of pneumonia on computed tomography (CT). None of them had visited the Huanan Seafood Wholesale Market in Wuhan within 14 days before symptom onset. Patients E, I, and P required admission to intensive care units, whereas the others had mild-to-moderate illness. Secondary infections were detected in close contacts of Patients E, I, and P. Patient E worked in Wuhan and visited his wife (Patient L), mother (Patient D), and a friend (Patient Z) in Zhuhai on January 17. Symptoms developed in Patients L and D on January 20 and January 22, respectively, with viral RNA detected in their nasal and throat swabs soon after symptom onset. Patient Z reported no clinical symptoms, but his nasal swabs (cycle threshold [Ct] values, 22 to 28) and throat swabs (Ct values, 30 to 32) tested positive on days 7, 10, and 11 after contact. A CT scan of Patient Z that was obtained on February 6 was unremarkable. Patients I and P lived in Wuhan and visited their daughter (Patient H) in Zhuhai on January 11 when their symptoms first developed. Fever developed in Patient H on January 17, with viral RNA detected in nasal and throat swabs on day 1 after symptom onset. We analyzed the viral load in nasal and throat swabs obtained from the 17 symptomatic patients in relation to day of onset of any symptoms (Figure 1C). Higher viral loads (inversely related to Ct value) were detected soon after symptom onset, with higher viral loads detected in the nose than in the throat. Our analysis suggests that the viral nucleic acid shedding pattern of patients infected with SARS-CoV-2 resembles that of patients with influenza 4 and appears different from that seen in patients infected with SARS-CoV. 3 The viral load that was detected in the asymptomatic patient was similar to that in the symptomatic patients, which suggests the transmission potential of asymptomatic or minimally symptomatic patients. These findings are in concordance with reports that transmission may occur early in the course of infection 5 and suggest that case detection and isolation may require strategies different from those required for the control of SARS-CoV. How SARS-CoV-2 viral load correlates with culturable virus needs to be determined. Identification of patients with few or no symptoms and with modest levels of detectable viral RNA in the oropharynx for at least 5 days suggests that we need better data to determine transmission dynamics and inform our screening practices.
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            Rational use of face masks in the COVID-19 pandemic

            Since the outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that caused coronavirus disease 2019 (COVID-19), the use of face masks has become ubiquitous in China and other Asian countries such as South Korea and Japan. Some provinces and municipalities in China have enforced compulsory face mask policies in public areas; however, China's national guideline has adopted a risk-based approach in offering recommendations for using face masks among health-care workers and the general public. We compared face mask use recommendations by different health authorities (panel ). Despite the consistency in the recommendation that symptomatic individuals and those in health-care settings should use face masks, discrepancies were observed in the general public and community settings.1, 2, 3, 4, 5, 6, 7, 8 For example, the US Surgeon General advised against buying masks for use by healthy people. One important reason to discourage widespread use of face masks is to preserve limited supplies for professional use in health-care settings. Universal face mask use in the community has also been discouraged with the argument that face masks provide no effective protection against coronavirus infection. Panel Recommendations on face mask use in community settings WHO 1 • If you are healthy, you only need to wear a mask if you are taking care of a person with suspected SARS-CoV-2 infection. China 2 • People at moderate risk* of infection: surgical or disposable mask for medical use. • People at low risk† of infection: disposable mask for medical use. • People at very low risk‡ of infection: do not have to wear a mask or can wear non-medical mask (such as cloth mask). Hong Kong 3 • Surgical masks can prevent transmission of respiratory viruses from people who are ill. It is essential for people who are symptomatic (even if they have mild symptoms) to wear a surgical mask. • Wear a surgical mask when taking public transport or staying in crowded places. It is important to wear a mask properly and practice good hand hygiene before wearing and after removing a mask. Singapore 4 • Wear a mask if you have respiratory symptoms, such as a cough or runny nose. Japan 5 • The effectiveness of wearing a face mask to protect yourself from contracting viruses is thought to be limited. If you wear a face mask in confined, badly ventilated spaces, it might help avoid catching droplets emitted from others but if you are in an open-air environment, the use of face mask is not very efficient. USA 6 • Centers for Disease Control and Prevention does not recommend that people who are well wear a face mask (including respirators) to protect themselves from respiratory diseases, including COVID-19. • US Surgeon General urged people on Twitter to stop buying face masks. UK 7 • Face masks play a very important role in places such as hospitals, but there is very little evidence of widespread benefit for members of the public. Germany 8 • There is not enough evidence to prove that wearing a surgical mask significantly reduces a healthy person's risk of becoming infected while wearing it. According to WHO, wearing a mask in situations where it is not recommended to do so can create a false sense of security because it might lead to neglecting fundamental hygiene measures, such as proper hand hygiene. However, there is an essential distinction between absence of evidence and evidence of absence. Evidence that face masks can provide effective protection against respiratory infections in the community is scarce, as acknowledged in recommendations from the UK and Germany.7, 8 However, face masks are widely used by medical workers as part of droplet precautions when caring for patients with respiratory infections. It would be reasonable to suggest vulnerable individuals avoid crowded areas and use surgical face masks rationally when exposed to high-risk areas. As evidence suggests COVID-19 could be transmitted before symptom onset, community transmission might be reduced if everyone, including people who have been infected but are asymptomatic and contagious, wear face masks. Recommendations on face masks vary across countries and we have seen that the use of masks increases substantially once local epidemics begin, including the use of N95 respirators (without any other protective equipment) in community settings. This increase in use of face masks by the general public exacerbates the global supply shortage of face masks, with prices soaring, 9 and risks supply constraints to frontline health-care professionals. As a response, a few countries (eg, Germany and South Korea) banned exportation of face masks to prioritise local demand. 10 WHO called for a 40% increase in the production of protective equipment, including face masks. 9 Meanwhile, health authorities should optimise face mask distribution to prioritise the needs of frontline health-care workers and the most vulnerable populations in communities who are more susceptible to infection and mortality if infected, including older adults (particularly those older than 65 years) and people with underlying health conditions. People in some regions (eg, Thailand, China, and Japan) opted for makeshift alternatives or repeated usage of disposable surgical masks. Notably, improper use of face masks, such as not changing disposable masks, could jeopardise the protective effect and even increase the risk of infection. Consideration should also be given to variations in societal and cultural paradigms of mask usage. The contrast between face mask use as hygienic practice (ie, in many Asian countries) or as something only people who are unwell do (ie, in European and North American countries) has induced stigmatisation and racial aggravations, for which further public education is needed. One advantage of universal use of face masks is that it prevents discrimination of individuals who wear masks when unwell because everybody is wearing a mask. It is time for governments and public health agencies to make rational recommendations on appropriate face mask use to complement their recommendations on other preventive measures, such as hand hygiene. WHO currently recommends that people should wear face masks if they have respiratory symptoms or if they are caring for somebody with symptoms. Perhaps it would also be rational to recommend that people in quarantine wear face masks if they need to leave home for any reason, to prevent potential asymptomatic or presymptomatic transmission. In addition, vulnerable populations, such as older adults and those with underlying medical conditions, should wear face masks if available. Universal use of face masks could be considered if supplies permit. In parallel, urgent research on the duration of protection of face masks, the measures to prolong life of disposable masks, and the invention on reusable masks should be encouraged. Taiwan had the foresight to create a large stockpile of face masks; other countries or regions might now consider this as part of future pandemic plans. © 2020 Sputnik/Science Photo Library 2020 Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
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              Face masks for the public during the covid-19 crisis

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                Author and article information

                Journal
                J Glob Health
                J Glob Health
                JGH
                Journal of Global Health
                International Society of Global Health
                2047-2978
                2047-2986
                December 2020
                28 July 2020
                : 10
                : 2
                : 020311
                Affiliations
                [1]Department of Health Promotion and Community Health, Faculty of Health Sciences, American University of Beirut, Lebanon
                Author notes
                Correspondence to:
Tamar Kabakian-Khasholian
Department of Health Promotion and Community
Health Faculty of Health Sciences, American University of Beirut
POBOX 11-0236, Riad El Solh 1107
2020 Beirut, Lebanon tk00@ 123456aub.edu.lb
                Article
                jogh-10-020311
                10.7189/jogh.10.020311
                7535134
                07a204ca-50dd-4ddb-a541-bf2728905b3f
                Copyright © 2020 by the Journal of Global Health. All rights reserved.

                This work is licensed under a Creative Commons Attribution 4.0 International License.

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