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      Cancer mortality in Brazil : Temporal Trends and Predictions for the Year 2030

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          Abstract

          Cancer is currently in the spotlight due to their heavy responsibility as main cause of death in both developed and developing countries. Analysis of the epidemiological situation is required as a support tool for the planning of public health measures for the most vulnerable groups. We analyzed cancer mortality trends in Brazil and geographic regions in the period 1996 to 2010 and calculate mortality predictions for the period 2011 to 2030.

          This is an epidemiological, demographic-based study that utilized information from the Mortality Information System on all deaths due to cancer in Brazil. Mortality trends were analyzed by the Joinpoint regression, and Nordpred was utilized for the calculation of predictions.

          Stability was verified for the female (annual percentage change [APC] = 0.4%) and male (APC = 0.5%) sexes. The North and Northeast regions present significant increasing trends for mortality in both sexes. Until 2030, female mortality trends will not present considerable variations, but there will be a decrease in mortality trends for the male sex. There will be increases in mortality rates until 2030 for the North and Northeast regions, whereas reductions will be verified for the remaining geographic regions. This variation will be explained by the demographic structure of regions until 2030.

          There are pronounced regional and sex differences in cancer mortality in Brazil, and these discrepancies will continue to increase until the year 2030, when the Northeast region will present the highest cancer mortality rates in Brazil.

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          The global burden of cancer: priorities for prevention

          Despite decreases in the cancer death rates in high-resource countries, such as the USA, the number of cancer cases and deaths is projected to more than double worldwide over the next 20–40 years. Cancer is now the third leading cause of death, with >12 million new cases and 7.6 million cancer deaths estimated to have occurred globally in 2007 (1). By 2030, it is projected that there will be ∼26 million new cancer cases and 17 million cancer deaths per year. The projected increase will be driven largely by growth and aging of populations and will be largest in low- and medium-resource countries. Under current trends, increased longevity in developing countries will nearly triple the number of people who survive to age 65 by 2050. This demographic shift is compounded by the entrenchment of modifiable risk factors such as smoking and obesity in many low-and medium-resource countries and by the slower decline in cancers related to chronic infections (especially stomach, liver and uterine cervix) in economically developing than in industrialized countries. This paper identifies several preventive measures that offer the most feasible approach to mitigate the anticipated global increase in cancer in countries that can least afford it. Foremost among these are the need to strengthen efforts in international tobacco control and to increase the availability of vaccines against hepatitis B and human papilloma virus in countries where they are most needed.
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            Envelhecimento populacional contemporâneo: demandas, desafios e inovações

            O estudo discute as conseqüências sociais e, particularmente, da saúde, decorrentes da ampliação do número de idosos no Brasil em um curto período. Foram utilizados dados da Pesquisa Nacional por Amostra de Domicílios, de 1998 e 2003, que indicam melhoria das condições de saúde dos idosos e uma distribuição de doença crônica semelhante para todos os grupos de renda. Se, por um lado, os idosos apresentam maior carga de doenças e incapacidades, e usam mais os serviços de saúde, por outro, os modelos vigentes de atenção à saúde do idoso se mostram ineficientes e de alto custo, reclamando estruturas criativas e inovadoras, como os centros de convivência com avaliação e tratamento de saúde. A agenda prioritária da política pública brasileira deveria priorizar a manutenção da capacidade funcional dos idosos, com monitoramento das condições de saúde, com ações preventivas e diferenciadas de saúde e de educação, com cuidados qualificados e atenção multidimensional e integral.
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              Cancer statistics in Korea: incidence, mortality, survival and prevalence in 2010.

              This article gives an overview of nationwide cancer statistics, including incidence, mortality, survival and prevalence, and their trends in Korea based on 2010 cancer incidence data. Incidence data from 1993 to 2010 were obtained from the Korea National Cancer Incidence Database, and vital status was followed until 31 December 2011. Mortality data from 1983 to 2010 were obtained from Statistics Korea. Crude and age-standardized rates for incidence, mortality, prevalence, and relative survival were calculated. In total, 202,053 cancer cases and 72,046 cancer deaths occurred during 2010, and 960,654 prevalent cancer cases were identified in Korea as of 1 January 2011. The incidence of all cancers combined showed an annual increase of 3.3% from 1999 to 2010. The incidences of liver and cervical cancers have decreased while those of thyroid, breast, prostate and colorectal cancers have increased. Notably, thyroid cancer, which is the most common cancer in Korea, increased by 24.2% per year rapidly in both sexes. The mortality of all cancers combined showed a decrease by 2.7% annually from 2002 to 2010. Five-year relative survival rates of patients who were diagnosed with cancer from 2006 to 2011 had improved by 22.9% compared with those from 1993 to 1995. While the overall cancer incidence in Korea has increased rapidly, age-standardized cancer mortality rates have declined since 2002 and survival has improved.
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                Author and article information

                Journal
                Medicine (Baltimore)
                Medicine (Baltimore)
                MEDI
                Medicine
                Wolters Kluwer Health
                0025-7974
                1536-5964
                April 2015
                24 April 2015
                : 94
                : 16
                : e746
                Affiliations
                From the Graduate Program in Collective Health (IRB); Department of Collective Health (DLBDS); Department of Odontology, Federal University of Rio Grande do Norte, Natal, Brazil (IDCCC); Department of Microbiology, Preventive Medicine and Public Health, University of Zaragoza, Zaragoza, Spain (MMB).
                Author notes
                Correspondence: Isabelle R. Barbosa, Department of Odontology, Graduate Program in Collective Health, Federal University of Rio Grande do Norte, Avenida Senador Salgado Filho 1787, CEP 59010-000, Lagoa Nova, Natal-RN, Brazil (e-mail: isabelleribeiro@ 123456oi.com.br ).
                Article
                00746
                10.1097/MD.0000000000000746
                4602680
                25906105
                0837e47f-80c1-4156-add6-80682fd54989
                Copyright © 2015 Wolters Kluwer Health, Inc. All rights reserved.

                This is an open access article distributed under the Creative Commons Attribution License 4.0, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. http://creativecommons.org/licenses/by/4.0

                History
                : 13 January 2015
                : 4 March 2015
                : 17 March 2015
                Categories
                4400
                Article
                Observational Study
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