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      Fixed or random effects meta-analysis? Common methodological issues in systematic reviews of effectiveness.

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          Abstract

          Systematic review aims to systematically identify, critically appraise, and summarize all relevant studies that match predefined criteria and answer predefined questions. The most common type of systematic review is that assessing the effectiveness of an intervention or therapy. In this article, we discuss some of the common methodological issues that arise when conducting systematic reviews and meta-analyses of effectiveness data, including issues related to study designs, meta-analysis, and the use and interpretation of effect sizes.

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          Author and article information

          Journal
          Int J Evid Based Healthc
          International journal of evidence-based healthcare
          Ovid Technologies (Wolters Kluwer Health)
          1744-1609
          1744-1595
          Sep 2015
          : 13
          : 3
          Affiliations
          [1 ] The Joanna Briggs Institute, Faculty of Health Sciences, The University of Adelaide, Adelaide, 115 Grenfell Street, South Australia 5000, Australia.
          Article
          01787381-201509000-00012
          10.1097/XEB.0000000000000065
          26355603
          08387598-f710-458b-8e0d-6a3156815e1c
          History

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