Randomized Trial of Periodic Presumptive Treatment With High-Dose Intravaginal Metronidazole and Miconazole to Prevent Vaginal Infections in HIV-negative Women.

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Abstract

Vaginal infections are common, frequently recur, and may increase women's risk for sexually transmitted infections (STIs). We tested the efficacy of a novel regimen to prevent recurrent vaginal infections.

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Journal

Journal ID (iso-abbrev): J. Infect. Dis.

Title: The Journal of infectious diseases

Publisher: Oxford University Press (OUP)

ISSN (Electronic): 1537-6613

ISSN (Print): 0022-1899

Publication date (Electronic): Jun 15 2015

Volume: 211

Issue: 12

Affiliations

[1 ] Department of Medicine Department of Epidemiology Department of Global Health, University of Washington Institute of Tropical and Infectious Diseases.

[2 ] Department of Global Health, University of Washington Department of Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington.

[3 ] Department of Biostatistics, University of Arkansas for Medical Sciences, Little Rock.

[4 ] Kenya AIDS Vaccine Initiative, University of Nairobi.

[5 ] Institute of Tropical and Infectious Diseases.

[6 ] Division of Infectious Diseases, University of Alabama at Birmingham.

[7 ] FHI360, Durham, North Carolina.

[8 ] Embil Pharmaceutical Company, Istanbul, Turkey.

Article

Publisher Item ID: jiu818

DOI: 10.1093/infdis/jiu818

PMC ID: 4836721

PubMed ID: 25526757

SO-VID: 08584257-9ae2-4d7b-9abd-ceff61610d80

History

Keywords: Trichomonas vaginalis,bacterial vaginosis,metronidazole,miconazole,periodic presumptive treatment,vulvovaginal candidiasis

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Keywords: Trichomonas vaginalis, bacterial vaginosis, metronidazole, miconazole, periodic presumptive treatment, vulvovaginal candidiasis

Randomized Trial of Periodic Presumptive Treatment With High-Dose Intravaginal Metronidazole and Miconazole to Prevent Vaginal Infections in HIV-negative Women.

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Abstract

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Bacterial vaginosis and biofilm

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