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      Pancreatic Islet Cell Tumors Metastatic to the Liver: Treatment by Hepatic Artery Chemo-Embolization


      Hormone Research in Paediatrics

      S. Karger AG

      Apudoma, Liver neoplasms, Metastases, Therapeutic embolization

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          The embolization of hepatic metastases of pancreatic islet cell tumors achieves a tumor necrosis without liver failure owing to double hepatic blood supply. The arterial chemotherapy performed at the same time delivers a large amount of cytotoxic agent directly into the tumor. Tumor bulk reducing and decreasing of production of pharmacologically active substances may be obtained to some degree. Although an objective documentation of the therapeutic effect is difficult to obtain, several series emphasize that the embolization provides a partial and transient palliative remission. Therefore, the chemo-embolization should be included in a multidisciplinary approach of metastatic endocrine malignancies in combination with surgical resection, systemic antineoplastic chemotherapy, and antihormonal therapy.

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          Author and article information

          Horm Res Paediatr
          Hormone Research in Paediatrics
          S. Karger AG
          02 December 2008
          : 32
          : 1-3
          : 77-79
          Services de Radiologie Digestive et de Gastroentérologie, Hôpital Edouard-Herriot, Lyon, France
          181250 Horm Res 1989;32:77–79
          © 1989 S. Karger AG, Basel

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          Page count
          Pages: 3
          Peptide Hormone Secreting Tumors


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