For Publishers
DiscoveryMetadataPeer reviewHostingPublishing
For Researchers
JoinPublishReviewCollect
Register
Blog
About
Search
Advanced search
My ScienceOpen
Search
For Publishers
For Researchers
Blog
About
13
views
0
references
 Top references
cited by
0
    
0 reviews
 Review
0
comments
 Comment
0
recommends
+1 Recommend
1 collections
    0
    shares
      27
      similar
       All similar
      Are you tired of sifting through news that doesn't interest you?
      Personalize your Karger newsletter today and get only the news that matters to you!

      Sign up

      • Record: found
      • Abstract: found
      • Article: found

      Efficacy of Paroxetine in Primary Palmoplantar Hyperhidrosis Occurring with Juvenile Myoclonic Epilepsy

      case-report

      Read this article at

      ScienceOpenPublisherPubMed
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Primary palmoplantar hyperhidrosis (PPH) is believed to be a dysfunction of emotional sweating, with an estimated prevalence of around 3%. Several treatment options including topical antiperspirants, tap water iontophoresis, botulinum toxin injections, oral anticholinergics, and tricyclic antidepressants are available, each with a significant adverse event profile. For the first time, we report a PPH patient with comorbid juvenile myoclonic epilepsy (JME) treated successfully with a combination of paroxetine and divalproex sodium. Paroxetine resulted in improvement in PPH, possibly through its anticholinergic and/or noradrenergic actions. Though the occurrence of PPH and JME together seems to be a chance association, some common frontal lobe mechanisms may be involved that need to be explored further.

          Related collections

          Author and article information

          Journal
          Journal ID (publisher-id): DRM
          Journal ID (nlm-ta): Dermatology
          Journal ID (doi): 10.1159/issn.1018-8665
          Title: Dermatology
          Publisher: S. Karger AG
          ISSN (Print): 1018-8665
          ISSN (Electronic): 1421-9832
          Publication date Subscription-year: 2011
          Publication date (Print): December 2011
          Publication date (Electronic): 26 August 2011
          Volume: 223
          Issue: 3
          Pages: 193-195
          Affiliations
          aSchool of Psychology, Bangor University, Bangor, UK; bDepartment of Psychiatry, Silchar Medical College and Hospital, Assam, and cDepartment of Psychiatry, Central Institute of Psychiatry, Ranchi, India
          Author notes
          *Mohammad Zia Ul Haq Katshu, School of Psychology, Brigantia Building, Bangor University, Bangor, LL57 2AS (UK), Tel. +44 12 4838 8680, E-Mail drziaulhaq@gmail.com
          Article
          Publisher ID: 330559 Other ID: Dermatology 2011;223:193–195
          DOI: 10.1159/000330559
          PubMed ID: 21876340
          SO-VID: 086a1585-163d-4e3e-acb7-aabec2fb7081
          Copyright © © 2011 S. Karger AG, Basel
          License:

          Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

          History
          Date received : 28 April 2011
          Date accepted : 21 June 2011
          Page count
          Pages: 3
          Categories
          Subject: Case and Review

          ScienceOpen disciplines: Oncology & Radiotherapy,Pathology,Surgery,Dermatology,Pharmacology & Pharmaceutical medicine
          Keywords: Emotional sweating,Juvenile myoclonic epilepsy,Paroxetine,Thermoregulatory sweating,Primary palmoplantar hyperhidrosis
          Data availability:
          ScienceOpen disciplines: Oncology & Radiotherapy, Pathology, Surgery, Dermatology, Pharmacology & Pharmaceutical medicine
          Keywords: Emotional sweating, Juvenile myoclonic epilepsy, Paroxetine, Thermoregulatory sweating, Primary palmoplantar hyperhidrosis

          Comments

          Comment on this article