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      Nanomaterials for the treatment of bacterial biofilms

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          Abstract

          Treatment of biofilm-associated infections is challenging, requiring the development of new therapeutic strategies. In this Viewpoint, we discuss the use of nanoparticle-based systems as active therapeutic agents and as vehicles to transport drugs to the site of infection. These applications require understanding of the surface interactions of nanoparticles with bacteria/biofilms, an aspect that we likewise summarize.

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          Author and article information

          Journal
          101654580
          43689
          ACS Infect Dis
          ACS Infect Dis
          ACS infectious diseases
          2373-8227
          6 March 2018
          21 October 2015
          08 January 2016
          13 March 2018
          : 2
          : 1
          : 3-4
          Affiliations
          Department of Chemistry, University of Massachusetts-Amherst, 710 North Pleasant Street, Amherst, Massachusetts, 01003, USA
          Author notes
          [* ]Address correspondence to rotello@ 123456chem.umass.edu
          Article
          PMC5848070 PMC5848070 5848070 nihpa947945
          10.1021/acsinfecdis.5b00116
          5848070
          27622944
          08715e14-9dbc-4a97-9a00-b7bd26399c10
          History
          Categories
          Article

          Nanoparticles,Surface Functionalization,Antimicrobial,Membrane Disruption

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